Target Details
| UniProt AC | P62873 |
|---|---|
| Gene Symbol | GNB1 |
| Protein Name | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF25391 (WD40_Gbeta) |
Summary
- Multi-target molecules 2
- Clinical molecules 0
- Avg pChEMBL 6.58
KEGG Pathways (22)
- Alcoholism
- Apelin signaling pathway
- Chemokine signaling pathway
- Cholinergic synapse
- Circadian entrainment
- Dopaminergic synapse
- GABAergic synapse
- Glutamatergic synapse
- Hormone signaling
- Human cytomegalovirus infection
- Human immunodeficiency virus 1 infection
- Kaposi sarcoma-associated herpesvirus infection
- Morphine addiction
- Neuroactive ligand signaling
- Olfactory transduction
- PI3K-Akt signaling pathway
- Pathways in cancer
- Phototransduction
- Ras signaling pathway
- Relaxin signaling pathway
- Retrograde endocannabinoid signaling
- Serotonergic synapse
Associated Diseases (2)
Top Co-occurrence Targets
- GNG2 2 shared
Active Molecules (2)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
RPZCQYBKVFZDLR
|
7.0 | IC50 | 2 | — | |
BAKPKHOMBCGIMC
|
6.2 | IC50 | 2 | — |