Target Details
| UniProt AC | P62593 |
|---|---|
| Gene Symbol | bla |
| Protein Name | Beta-lactamase TEM |
| Organism | Escherichia coli |
| Entry Name | |
| Organism Category | Pathogen |
| Pfam Domains | PF13354 (Beta-lactamase2) |
Summary
- Multi-target molecules 106
- Clinical molecules 0
- Avg pChEMBL 7.66
Top Co-occurrence Targets
- ampC 51 shared
- ampC 44 shared
- OXA-48 34 shared
- ccrA 34 shared
- nmcA 12 shared
- blaZ 9 shared
- imiA 4 shared
- OXA-1 2 shared
- blaCTX-M-9a 1 shared
- blaCTX-M-14 1 shared
Active Molecules (106)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
DMEYZPJEFHGESJ
|
9.4 | IC50 | 4 | — | |
MTRYCRPKNWRHLE
|
9.4 | IC50 | 4 | — | |
KHQWVYGFKAJISE
|
9.3 | IC50 | 3 | — | |
DVLLKFBRONEGAN
|
9.1 | IC50 | 2 | — | |
IBSSBUWAVGFIIX
|
9.0 | IC50 | 4 | — | |
KIBIIJXINDFXSV
|
9.0 | IC50 | 4 | — | |
NCGUZWKSZMMNCP
|
9.0 | IC50 | 4 | — | |
XFARUGBBAMTOCU
|
9.0 | IC50 | 4 | — | |
YJSNNWLWFJHTLH
|
9.0 | IC50 | 4 | — | |
YRWWCWBDXGMNHI
|
9.0 | IC50 | 4 | — | |
HBJXCJGYADJSFE
|
8.9 | IC50 | 3 | — | |
QYPIGCMIMCHYCS
|
8.8 | IC50 | 3 | — | |
NDCUAPJVLWFHHB
|
8.7 | IC50 | 8 | — | |
XTADYNGCKRLHLU
|
8.7 | IC50 | 4 | — | |
ZKKACLLQVNCVQU
|
8.7 | IC50 | 4 | — | |
FMUADCKWHCHFKD
|
8.5 | IC50 | 3 | — | |
IKGZFJCMJFERPR
|
8.5 | IC50 | 2 | — | |
IKGZFJCMJFERPR
|
8.5 | IC50 | 2 | — | |
QIAAAFQSVXOMRB
|
8.5 | IC50 | 3 | — | |
UAILHDKDBBFHDN
|
8.5 | IC50 | 3 | — | |
CZCMDCKIUIXEQC
|
8.5 | IC50 | 3 | — | |
VZTMHDMZOMWRDY
|
8.5 | IC50 | 2 | — | |
ZEICLMMMMGQHIK
|
8.5 | IC50 | 3 | — | |
DWYDARUUOLMALM
|
8.4 | IC50 | 4 | — | |
MRXVYOLTKNEJHK
|
8.4 | IC50 | 4 | — | |
HBJXCJGYADJSFE
|
8.4 | IC50 | 3 | — | |
KODABZGSORMKQV
|
8.3 | IC50 | 4 | — | |
LQVZDTYWLLBGHZ
|
8.3 | IC50 | 2 | — | |
SZEAVITUDYBJGA
|
8.3 | IC50 | 4 | — | |
HXVDRENWBJTNFL
|
8.2 | IC50 | 3 | — | |
RRXLDJWFWBTXTP
|
8.2 | IC50 | 4 | — | |
SVACAECNLJKLOK
|
8.2 | IC50 | 3 | — | |
XPRZVSWHOFCGHP
|
8.2 | IC50 | 2 | — | |
HUPHEXATWXVGJT
|
8.1 | IC50 | 3 | — | |
RLOBCNKTHMNWDX
|
8.1 | IC50 | 3 | — | |
AAJNAPQWOPAZAE
|
8.1 | IC50 | 3 | — | |
OXWWPWZFBQZZPH
|
8.1 | IC50 | 3 | — | |
ICRJCLPRVQCDKT
|
8.0 | IC50 | 3 | — | |
JTXLOXAHJKZYOH
|
8.0 | IC50 | 4 | — | |
ZQZVENIYZGCSFN
|
8.0 | IC50 | 3 | — | |
ZZWPJCNMJSBJDZ
|
7.9 | IC50 | 2 | — | |
FEKDJDOMDQNFAM
|
7.8 | IC50 | 3 | — | |
FINRLGAWOGFDKT
|
7.8 | IC50 | 3 | — | |
FUPMZGCETKRXTR
|
7.7 | IC50 | 2 | — | |
NCXKBKBIIBQZIH
|
7.7 | IC50 | 3 | — | |
HBJXCJGYADJSFE
|
7.7 | IC50 | 3 | — | |
NZNHTQCXWOAKDT
|
7.7 | IC50 | 2 | — | |
DVGGIJLCNIHENJ
|
7.7 | IC50 | 3 | — | |
KYVATCVZAZHVGK
|
7.7 | IC50 | 2 | — | |
QEYQIONWPOMBON
|
7.7 | IC50 | 2 | — |