Target Details
| UniProt AC | P61812 |
|---|---|
| Gene Symbol | TGFB2 |
| Protein Name | Transforming growth factor beta-2 proprotein |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00019 (TGF_beta) PF00688 (TGFb_propeptide) |
Summary
- Multi-target molecules 2
- Clinical molecules 0
- Avg pChEMBL 7.8
KEGG Pathways (31)
- AGE-RAGE signaling pathway in diabetic complications
- Amoebiasis
- Cell cycle
- Cellular senescence
- Chagas disease
- Chronic myeloid leukemia
- Colorectal cancer
- Cytokine-cytokine receptor interaction
- Diabetic cardiomyopathy
- Dilated cardiomyopathy
- FoxO signaling pathway
- Gastric cancer
- Hepatitis B
- Hepatocellular carcinoma
- Hippo signaling pathway
- Human T-cell leukemia virus 1 infection
- Hypertrophic cardiomyopathy
- Inflammatory bowel disease
- Leishmaniasis
- MAPK signaling pathway
- Malaria
- MicroRNAs in cancer
- Osteoclast differentiation
- Pancreatic cancer
- Pathways in cancer
- Proteoglycans in cancer
- Renal cell carcinoma
- Rheumatoid arthritis
- TGF-beta signaling pathway
- Toxoplasmosis
- Tuberculosis
Associated Diseases (3)
Active Molecules (2)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
NIQVUPWBHUGPKD
|
8.4 | IC50 | 2 | — | |
IVRXNBXKWIJUQB
|
7.2 | IC50 | 10 | — |