Target Details
| UniProt AC | P61073 |
|---|---|
| Gene Symbol | CXCR4 |
| Protein Name | C-X-C chemokine receptor type 4 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00001 (7tm_1) PF12109 (CXCR4_N) |
Summary
- Multi-target molecules 57
- Clinical molecules 0
- Avg pChEMBL 7.21
KEGG Pathways (14)
- Axon guidance
- Calcium signaling pathway
- Chemokine signaling pathway
- Cytokine-cytokine receptor interaction
- Endocytosis
- Human cytomegalovirus infection
- Human immunodeficiency virus 1 infection
- Intestinal immune network for IgA production
- Leukocyte transendothelial migration
- Pathways in cancer
- Regulation of actin cytoskeleton
- Viral life cycle - HIV-1
- Viral protein interaction with cytokine and cytokine receptor
- Virion - Human immunodeficiency virus
Associated Diseases (1)
Active Molecules (57)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
GSKIEMCFCQSCTJ
|
6.5 | IC50 | 2 | — | |
MUQGXMRSNYTSLA
|
6.5 | IC50 | 2 | — | |
SIMHCJVBDXBOGC
|
6.5 | IC50 | 3 | — | |
VWSXKWXISJLOQM
|
6.4 | IC50 | 6 | — | |
CFJSRSLPNHMHBB
|
6.3 | IC50 | 2 | — | |
LBNCYBAXRNMAKW
|
6.2 | IC50 | 3 | — | |
ZEEABZKRGAFENX
|
6.1 | IC50 | 3 | — |