Target Details
| UniProt AC | P60953 |
|---|---|
| Gene Symbol | CDC42 |
| Protein Name | Cell division control protein 42 homolog |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00071 (Ras) |
Summary
- Multi-target molecules 16
- Clinical molecules 0
- Avg pChEMBL 6.56
KEGG Pathways (34)
- AGE-RAGE signaling pathway in diabetic complications
- Adherens junction
- Axon guidance
- Bacterial invasion of epithelial cells
- Cadherin signaling
- Chemokine signaling pathway
- Endocytosis
- Epithelial cell signaling in Helicobacter pylori infection
- Fc gamma R-mediated phagocytosis
- Focal adhesion
- GnRH signaling pathway
- Human papillomavirus infection
- IgSF CAM signaling
- Integrin signaling
- Leukocyte transendothelial migration
- Lipid and atherosclerosis
- MAPK signaling pathway
- Neurotrophin signaling pathway
- Non-alcoholic fatty liver disease
- Pancreatic cancer
- Pathogenic Escherichia coli infection
- Pathways in cancer
- Proteoglycans in cancer
- Rap1 signaling pathway
- Ras signaling pathway
- Regulation of actin cytoskeleton
- Renal cell carcinoma
- Salmonella infection
- Shigellosis
- T cell receptor signaling pathway
- Tight junction
- VEGF signaling pathway
- Viral carcinogenesis
- Yersinia infection
Associated Diseases (1)
Active Molecules (16)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
MWKSRKSEWLRPBL
|
8.3 | Kd | 1075 | — | |
XBFAFSAUQFDEOK
|
7.3 | IC50 | 5 | — | |
LJCANTASZGYJLG
|
7.1 | IC50 | 4 | — | |
ZICSONYJRWNSDY
|
6.8 | Ki | 2 | — | |
GHPKDRSTACHPSP
|
6.6 | Ki | 2 | — | |
KOKQBQSCGZSNAT
|
6.5 | Ki | 2 | — | |
FYUPDLZDGMHHMW
|
6.5 | Ki | 2 | — | |
NCGFFHMGBKYDIK
|
6.4 | Ki | 2 | — | |
CDPZQJOQECZZJU
|
6.3 | Ki | 2 | — | |
CMWTZPSULFXXJA
|
6.3 | Ki | 2 | — | |
JFRFKHKFUJNKGC
|
6.2 | Ki | 2 | — | |
LNZYZAVDMUOOBN
|
6.2 | Ki | 3 | — | |
BVTSTKMBRXFWAP
|
6.2 | Ki | 4 | — | |
YEWYWWRBZDDFMO
|
6.0 | Ki | 4 | — | |
HEFNNWSXXWATRW
|
6.0 | Ki | 5 | — | |
OZWKMVRBQXNZKK
|
6.0 | IC50 | 2 | — |