Target Details
UniProt ACP56817
Gene SymbolBACE1
Protein NameBeta-secretase 1
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF00026 (Asp)
UniProt
Summary
  • Multi-target molecules 3,050
  • Clinical molecules 3
  • Avg pChEMBL 7.76
KEGG Pathways (1)
Top Co-occurrence Targets
Active Molecules (3,050)
InChIKey pChEMBL Type Targets Clinical
NOIMXCHFMTVPOT 9.5 IC50 2 —
VKRAAMXKFXEPOB 9.4 IC50 2 —
YRENRIQDWPMKAT 9.4 IC50 2 —
DFJSEZKHFLFIFH 9.4 IC50 2 —
NTTKBSISCOJNFJ 9.4 IC50 2 —
BPXPJXOEOWTZNG 9.4 IC50 2 —
SLPTVIUBRWQJEH 9.4 IC50 2 —
DFJSEZKHFLFIFH 9.4 IC50 2 —
RWZBXFGNRLPLGX 9.4 IC50 2 —
CJZWMPMJEVFVLS 9.4 IC50 2 —
GNZDJABHDPTECH 9.4 IC50 2 —
IOARFOYMAGIOGC 9.4 IC50 2 —
IPUJINDWAGRAHN 9.4 IC50 2 —
LWOMHNWWEBISDH 9.4 Ki 2 —
LZWVKJYCZYYGTR 9.4 IC50 2 —
NNXXSMMVPWTXHI 9.4 IC50 2 —
QVPZORXMLIMRNH 9.4 IC50 2 —
YLLZTZREIRJLLF 9.4 IC50 2 —
SWEXUURPDNWTQX 9.4 IC50 2 —
ZBNDWSQQCMROIW 9.4 IC50 2 —
ZOLASYMXTWTSAU 9.4 IC50 2 —
BJRJGMIEKMZBBT 9.4 IC50 2 —
DRTFEQDRPUEDQW 9.4 IC50 2 —
JJQWZCSBFBCGBJ 9.4 IC50 2 —
LYAMBLXFXWNHDJ 9.4 IC50 2 —
IFTNPMMPRFIXIV 9.4 IC50 2 —
IPUJINDWAGRAHN 9.4 IC50 2 —
DUSOLERPWPMKGR 9.3 IC50 2 —
JFFXUDFKLRIJQZ 9.3 IC50 2 —
JRHSAVDXFDXJJR 9.3 IC50 2 —
QAYRNKFHXPACGR 9.3 IC50 2 —
SWJMMSAVTXCDKG 9.3 IC50 2 —
BZXALZCLDWMBHI 9.3 IC50 2 —
CIUBGFWEPRANCU 9.3 IC50 2 —
HEVGFTALAULWIS 9.3 IC50 2 —
IBUFQSVABSYDJU 9.3 IC50 2 —
OCUOQVWUFZTWRS 9.3 IC50 2 —
JXMAOLUIOYLJRS 9.3 IC50 2 —
NHZQTQJHVKGWNO 9.3 IC50 2 —
STWWGQJQGWONHY 9.3 IC50 2 —
WFMNKRWAFUEYFB 9.3 IC50 2 —
DKOZJTFVKQAYQH 9.3 IC50 2 —
VPGJWPAEKCQKMY 9.3 Ki 2 —
HVZXHZGWIZNXDC 9.3 IC50 2 —
LDZLINYMNZPQDX 9.3 IC50 2 —
LDZLINYMNZPQDX 9.3 IC50 2 —
RABGKEGXXDDDFF 9.3 IC50 2 —
XHVCZVAGKAJWNP 9.3 IC50 2 —
ICKBNOOYPPDSCY 9.3 IC50 2 —
OKCROLBQEYZDEH 9.3 IC50 2 —
2D structure