Target Details
| UniProt AC | P55210 |
|---|---|
| Gene Symbol | CASP7 |
| Protein Name | Caspase-7 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00656 (Peptidase_C14) |
Summary
- Multi-target molecules 306
- Clinical molecules 0
- Avg pChEMBL 7.38
KEGG Pathways (14)
- Alzheimer disease
- Apoptosis
- Apoptosis - multiple species
- Cytosolic DNA-sensing pathway
- Efferocytosis
- Legionellosis
- Lipid and atherosclerosis
- Non-alcoholic fatty liver disease
- Pathogenic Escherichia coli infection
- Pathways in cancer
- Pathways of neurodegeneration - multiple diseases
- Pertussis
- Salmonella infection
- TNF signaling pathway
Active Molecules (306)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
ACPNTFIHYLLTHQ
|
6.1 | IC50 | 2 | — | |
DWGRSJBIHVFBFL
|
6.1 | IC50 | 3 | — | |
IYNNJMRCPJPTMI
|
6.0 | IC50 | 3 | — | |
MFWZBTUZXAYVJI
|
6.0 | IC50 | 2 | — | |
PZMBYHSWPUMKMR
|
6.0 | Ki | 3 | — | |
XTKUMMDOZMHSCM
|
6.0 | IC50 | 2 | — |