Target Details
| UniProt AC | P52333 |
|---|---|
| Gene Symbol | JAK3 |
| Protein Name | Tyrosine-protein kinase JAK3 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF18379 (FERM_F1) PF18377 (FERM_F2) PF17887 (Jak1_Phl) PF07714 (PK_Tyr_Ser-Thr) PF21990 (SH2_1) |
Summary
- Multi-target molecules 5,161
- Clinical molecules 45
- Avg pChEMBL 7.57
KEGG Pathways (15)
- Chemokine signaling pathway
- Epstein-Barr virus infection
- Hepatitis B
- Human T-cell leukemia virus 1 infection
- JAK-STAT signaling pathway
- Measles
- Necroptosis
- Non-small cell lung cancer
- PI3K-Akt signaling pathway
- Pathways in cancer
- Primary immunodeficiency
- Signaling pathways regulating pluripotency of stem cells
- Th1 and Th2 cell differentiation
- Th17 cell differentiation
- Viral carcinogenesis
Associated Diseases (1)