Target Details
| UniProt AC | P51957 |
|---|---|
| Gene Symbol | NEK4 |
| Protein Name | Serine/threonine-protein kinase Nek4 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00069 (Pkinase) |
Summary
- Multi-target molecules 71
- Clinical molecules 3
- Avg pChEMBL 6.6
Active Molecules (71)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
RJZDECGDCKOHBV
|
8.3 | Ki | 70 | — | |
FLEAYYMORDPWAJ
|
8.2 | Ki | 90 | — | |
MVJMMLFMPWITEJ
|
8.0 | Ki | 110 | — | |
GCBJDOWIQHMCMR
|
7.9 | Ki | 84 | — | |
YMIJUBCSOKSFRU
|
7.9 | Ki | 87 | — | |
OWRXHGAFWZFFCW
|
7.8 | Ki | 113 | — | |
JWQOJVOKBAAAAR
|
7.6 | Ki | 29 | — | |
LYNBNVBMAGDJRW
|
7.4 | Ki | 81 | — | |
LYADGAGFYYXXIO
|
7.3 | IC50 | 82 | — | |
KYACBMRLQMEIAI
|
7.3 | IC50 | 30 | — | |
RKUKAACYUCUJEE
|
7.3 | Ki | 58 | — | |
YEHCNYAQEBQCCS
|
7.2 | Ki | 74 | — | |
HKSZLNNOFSGOKW
|
7.1 | IC50 | 408 | — | |
MLGGUGPIWDHBAI
|
7.1 | IC50 | 10 | — | |
VGNKOJURPOHWJF
|
7.0 | Ki | 21 | — | |
CHTMRWQLNNRRFJ
|
6.9 | Ki | 70 | — | |
PNKALLUVKOKYHZ
|
6.9 | Ki | 32 | — | |
MLGGUGPIWDHBAI
|
6.8 | Ki | 33 | — | |
QAJPIJHWTGPUNZ
|
6.8 | Ki | 37 | — | |
QNABDSWBQJKBHK
|
6.8 | IC50 | 45 | — | |
UDFDIIVNIYWXDM
|
6.8 | Ki | 74 | — | |
LRZYYIZFBXFSJB
|
6.7 | Ki | 69 | — | |
NHHQJBCNYHBUSI
|
6.7 | Ki | 220 | — | |
RYYNGWLOYLRZLK
|
6.7 | Ki | 104 | — | |
WPHKIQPVPYJNAX
|
6.7 | IC50 | 81 | — | |
UEFCSGDOOJJXTN
|
6.6 | IC50 | 46 | — | |
FAYAUAZLLLJJGH
|
6.6 | Ki | 36 | Yes | |
GHMRUNOHAHJNNA
|
6.6 | Ki | 29 | — | |
MIKAKZKNMYZLDX
|
6.6 | Ki | 42 | — | |
NJPWCTYVEJIQBM
|
6.6 | Ki | 72 | — | |
VXYDJXMHISGSDA
|
6.6 | Ki | 59 | — | |
ZVWRFVCNQOECJS
|
6.6 | Ki | 71 | — | |
CKVWQORGCCEYHS
|
6.5 | Ki | 50 | — | |
LXVBELDBJGYFEM
|
6.5 | IC50 | 20 | — | |
UMTWTCVTRDYHQQ
|
6.5 | Ki | 56 | — | |
UYJNQQDJUOUFQJ
|
6.5 | Ki | 68 | — | |
XAYDUCQADQTDGX
|
6.5 | Ki | 12 | — | |
XOOAAYRIVATZNM
|
6.5 | Ki | 55 | — | |
NLUPJKQOKWBWFC
|
6.4 | Ki | 69 | — | |
ODPGGGTTYSGTGO
|
6.3 | Kd | 153 | — | |
NGFGTMFVWSDFPS
|
6.3 | IC50 | 32 | — | |
GCYXEGSPUDSZJY
|
6.3 | Ki | 82 | — | |
QYGMZFLXMWJYRJ
|
6.3 | Ki | 14 | — | |
OADRBDVURCEKRP
|
6.2 | Ki | 44 | — | |
PQNWNVWJXPSZFR
|
6.2 | Ki | 21 | — | |
QQWUGDVOUVUTOY
|
6.2 | Ki | 231 | Yes | |
XGMWRIIMIJPGBH
|
6.2 | Ki | 10 | — | |
AIQDZMUPVYDVLB
|
6.1 | Ki | 48 | — | |
FUMCKNCUEAQHCV
|
6.1 | Ki | 103 | — | |
JJJSCYSPSKBQAX
|
6.1 | Ki | 34 | — |