Target Details
| UniProt AC | P51955 |
|---|---|
| Gene Symbol | NEK2 |
| Protein Name | Serine/threonine-protein kinase Nek2 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00069 (Pkinase) |
Summary
- Multi-target molecules 120
- Clinical molecules 13
- Avg pChEMBL 6.6
Associated Diseases (1)
Active Molecules (120)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
CGECJCJUHCZZGO
|
9.0 | IC50 | 9 | — | |
BQODGOMHYSMCGK
|
8.5 | IC50 | 2 | — | |
ZCCPLJOKGAACRT
|
8.1 | Kd | 599 | — | |
KNACLJBHKVSTDL
|
7.9 | Ki | 40 | — | |
WPHKIQPVPYJNAX
|
7.9 | IC50 | 81 | — | |
FLEAYYMORDPWAJ
|
7.7 | Ki | 90 | — | |
GILNGUYOGYOZMP
|
7.7 | IC50 | 6 | — | |
RGNHKJWHFIPHIM
|
7.5 | Ki | 66 | — | |
CJQGLUJHMXCLQY
|
7.5 | IC50 | 11 | — | |
SWIVJTVGOIXUKC
|
7.5 | IC50 | 9 | — | |
DNZGEPPZYMAFLN
|
7.4 | IC50 | 2 | — | |
YDWMUCKJUNLURC
|
7.4 | IC50 | 24 | — | |
AKWNDIGQZONPHP
|
7.3 | IC50 | 2 | — | |
VKBFHTIUXUCYRQ
|
7.3 | IC50 | 8 | — | |
MCCCQFAOMZMZKE
|
7.2 | Ki | 52 | — | |
RBXYGQNZRVPDNB
|
7.2 | Ki | 34 | — | |
XHORJSJFHVABEA
|
7.2 | Ki | 49 | — | |
ZCCJKVBTHCOISJ
|
7.2 | Ki | 46 | — | |
ZGDYBJXDIXVTLV
|
7.2 | Ki | 54 | — | |
LLEOOSLUHRQCHZ
|
7.1 | IC50 | 2 | — | |
VKBFHTIUXUCYRQ
|
7.1 | Ki | 66 | — | |
XKZINYYXWJEYEL
|
7.1 | Ki | 37 | — | |
BIKYDWLMTPRSQL
|
7.0 | Ki | 50 | — | |
GJKVMXDBPDDFHI
|
7.0 | Ki | 27 | — | |
NKEUPUJTVALZIK
|
7.0 | Ki | 28 | — | |
AENKGHPUTMOKKU
|
7.0 | IC50 | 2 | — | |
VAARYSWULJUGST
|
7.0 | Kd | 119 | Yes | |
OWRXHGAFWZFFCW
|
6.9 | Ki | 113 | — | |
UIRCQOKSJDLYBB
|
6.9 | Ki | 50 | — | |
VCFDMLBPASGZTP
|
6.9 | Ki | 38 | — | |
XBYVOPRDASFDMY
|
6.9 | Ki | 42 | — | |
XJSFDMGICAWQFS
|
6.9 | Ki | 60 | — | |
LLEOOSLUHRQCHZ
|
6.9 | IC50 | 6 | — | |
IOGIUPJAOMXLRJ
|
6.8 | IC50 | 2 | — | |
CFIBXVQLBVNOHW
|
6.8 | Ki | 64 | — | |
OWFXKTOLFUQPDJ
|
6.8 | Ki | 36 | — | |
IBUMAHMUIWPTCV
|
6.7 | IC50 | 3 | — | |
KNARVZUUCLIBGV
|
6.7 | Ki | 33 | — | |
LVECPYVAIBNSRV
|
6.7 | Ki | 33 | — | |
MULNSLQVKKUPJN
|
6.7 | Ki | 41 | — | |
MVJMMLFMPWITEJ
|
6.7 | Ki | 110 | — | |
UGEJLCNSVIVALC
|
6.7 | Ki | 41 | — | |
ZMNWFTYYYCSSTF
|
6.7 | Ki | 18 | — | |
UQVVQLRAEQBLIK
|
6.7 | IC50 | 2 | — | |
MWKSRKSEWLRPBL
|
6.7 | Kd | 1075 | — | |
YPKLAWUGDWZBMV
|
6.6 | IC50 | 2 | — | |
JBRASADWXDKCLJ
|
6.6 | Ki | 22 | — | |
NRZYTPAJGVTKIM
|
6.6 | Ki | 38 | — | |
SRUYMJRFVGLQDV
|
6.6 | Ki | 37 | — | |
NHHQJBCNYHBUSI
|
6.6 | Kd | 220 | — |