Target Details
| UniProt AC | P51681 |
|---|---|
| Gene Symbol | CCR5 |
| Protein Name | C-C chemokine receptor type 5 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00001 (7tm_1) |
Summary
- Multi-target molecules 126
- Clinical molecules 2
- Avg pChEMBL 7.38
KEGG Pathways (11)
- Chemokine signaling pathway
- Cytokine-cytokine receptor interaction
- Endocytosis
- Human cytomegalovirus infection
- Human immunodeficiency virus 1 infection
- Kaposi sarcoma-associated herpesvirus infection
- Toxoplasmosis
- Viral carcinogenesis
- Viral life cycle - HIV-1
- Viral protein interaction with cytokine and cytokine receptor
- Virion - Human immunodeficiency virus
Associated Diseases (4)
Active Molecules (126)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
KDARXVILVONBOM
|
10.1 | IC50 | 2 | — | |
SXKNFGNGCSTXQU
|
9.5 | IC50 | 2 | — | |
SBQOMISLKZTLHT
|
9.4 | IC50 | 2 | — | |
UFZMURFKAOEOKB
|
9.2 | IC50 | 2 | — | |
PNDKCRDVVKJPKG
|
9.1 | IC50 | 2 | — | |
PNDKCRDVVKJPKG
|
9.1 | IC50 | 3 | — | |
QKMUXXQVPOBBPT
|
9.0 | Ki | 3 | — | |
XVOCHVRQMXWEQB
|
9.0 | Ki | 2 | — | |
RUGPFTCINDXZAE
|
8.9 | IC50 | 2 | — | |
OLUONKODHNDKJM
|
8.9 | IC50 | 2 | — | |
GSNHKUDZZFZSJB
|
8.9 | IC50 | 2 | — | |
NAYZSSQGIKJDGG
|
8.8 | IC50 | 2 | — | |
XNHZXMPLVSJQFK
|
8.8 | IC50 | 4 | — | |
UDRZSXGBJMNBJU
|
8.8 | IC50 | 2 | — | |
KFQMAIZBNWWGPO
|
8.6 | IC50 | 2 | — | |
NUJWKQSEJDYCDB
|
8.6 | IC50 | 4 | — | |
NCDCQNWXYJMYAZ
|
8.6 | IC50 | 2 | — | |
JWRNDENHFBRQCM
|
8.6 | Ki | 2 | — | |
HMBFXHIQISYDKM
|
8.5 | Ki | 4 | — | |
JBRPUKJNMGIQRP
|
8.5 | IC50 | 2 | — | |
ZILPZMJIIYWEIE
|
8.5 | IC50 | 2 | — | |
NIGNHDUWKZDZLS
|
8.5 | IC50 | 2 | — | |
CMVHFGNTABZQJU
|
8.4 | IC50 | 2 | — | |
DQWSENNLMPJNRJ
|
8.3 | IC50 | 2 | — | |
YFEPUDFZMYDTMF
|
8.3 | IC50 | 2 | — | |
KFPNMAHHOBQVHI
|
8.2 | IC50 | 2 | — | |
RQDGBNLSKUOAJD
|
8.2 | Ki | 3 | — | |
NTXQSFSEZXNHJY
|
8.1 | IC50 | 2 | — | |
PIYDNEWDZZFKKO
|
8.1 | IC50 | 2 | — | |
WXRJQYAAIDCOMB
|
8.0 | IC50 | 2 | — | |
KUOUHUKIBBTXEV
|
8.0 | Ki | 2 | — | |
MTBTXJDOIZCIGH
|
8.0 | IC50 | 2 | — | |
UMOFYSFQZJYWNT
|
8.0 | Ki | 2 | — | |
BUZVRSCZMYHLGQ
|
8.0 | Ki | 2 | — | |
LLEJRCRDMYBLEH
|
8.0 | IC50 | 2 | — | |
LULHPKFDNFSVFW
|
8.0 | Ki | 2 | — | |
QWZMAQRSGSBPHQ
|
8.0 | Ki | 2 | — | |
UGRYBQQJOKDQHB
|
7.8 | IC50 | 2 | — | |
DNPRHSLKGYTIJX
|
7.7 | IC50 | 2 | — | |
JGAMGZZJGJQWBX
|
7.7 | Ki | 2 | — | |
QJQMEUAVQLMKRZ
|
7.7 | IC50 | 2 | — | |
QOYZHUQEWFRBJB
|
7.7 | IC50 | 2 | — | |
QVDCSAIULQECDK
|
7.7 | Ki | 2 | — | |
HIEMJINKLJLCCH
|
7.7 | IC50 | 2 | — | |
KQHWUFNWNPCEGY
|
7.7 | Ki | 2 | — | |
VBONNDPACFTZMX
|
7.7 | IC50 | 2 | — | |
DEXJQUDODNDJEZ
|
7.7 | IC50 | 2 | — | |
OOGWCCRYNCAIBK
|
7.7 | IC50 | 2 | — | |
PEFVTWREQBVUOK
|
7.6 | IC50 | 2 | — | |
VBMPRCMEFUCQPO
|
7.6 | IC50 | 2 | — |