MMP15 — MultiTargetDB

Target Details

UniProt AC	`P51511`
Gene Symbol	MMP15
Protein Name	Matrix metalloproteinase-15
Organism	Homo sapiens
Entry Name
Organism Category	Human
Pfam Domains	PF11857 (DUF3377) PF00045 (Hemopexin) PF00413 (Peptidase_M10) PF01471 (PG_binding_1)

Summary

Multi-target molecules 14
Clinical molecules 13
Avg pChEMBL 7.46

KEGG Pathways (1)

Parathyroid hormone synthesis, secretion and action

Top Co-occurrence Targets

MMP2 14 shared
MMP16 13 shared
MMP9 13 shared
MMP14 12 shared
MMP17 11 shared
MMP12 11 shared
MMP1 11 shared
MMP26 9 shared
ADAM17 3 shared
MMP13 3 shared

Active Molecules (14)

InChIKey	pChEMBL	Type	Targets	Clinical
`OVUDWXYTKUKYAX`	8.4	IC50	9	Yes
`AYFCYVLVRYQGME`	8.2	IC50	8	—
`AYFCYVLVRYQGME`	8.2	IC50	9	Yes
`NITYDPDXAAFEIT`	8.2	IC50	20	Yes
`YVCCTHCWKOIESX`	7.8	IC50	8	Yes
`PFIFGQWOKBQYID`	7.7	IC50	9	Yes
`HFAGTNGCAZYYLZ`	7.7	Ki	13	Yes
`JOGYGVFUVCZABB`	7.5	IC50	9	Yes
`RILFWDKQYPJIOQ`	7.4	IC50	8	Yes
`DONMTDNLNMLOIC`	7.2	Ki	13	Yes
`YVJXBWDNNWDVMN`	6.9	IC50	9	Yes
`NOENPCOHNDAVLW`	6.7	IC50	7	Yes
`VVZFBVIPGIVQRI`	6.4	IC50	7	Yes
`ZJOQXNGTEXFLLO`	6.2	IC50	2	Yes