Target Details
| UniProt AC | P50993 |
|---|---|
| Gene Symbol | ATP1A2 |
| Protein Name | Sodium/potassium-transporting ATPase subunit alpha-2 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF13246 (Cation_ATPase) PF00689 (Cation_ATPase_C) PF00690 (Cation_ATPase_N) PF00122 (E1-E2_ATPase) |
Summary
- Multi-target molecules 134
- Clinical molecules 0
- Avg pChEMBL 6.93
KEGG Pathways (19)
- Adrenergic signaling in cardiomyocytes
- Aldosterone synthesis and secretion
- Aldosterone-regulated sodium reabsorption
- Bile secretion
- Carbohydrate digestion and absorption
- Cardiac muscle contraction
- Cytoskeleton in muscle cells
- Endocrine and other factor-regulated calcium reabsorption
- Gastric acid secretion
- Insulin secretion
- Mineral absorption
- Pancreatic secretion
- Protein digestion and absorption
- Proximal tubule bicarbonate reclamation
- Salivary secretion
- Thyroid hormone signaling pathway
- Thyroid hormone synthesis
- cAMP signaling pathway
- cGMP-PKG signaling pathway
Associated Diseases (3)