Target Details
| UniProt AC | P49768 |
|---|---|
| Gene Symbol | PSEN1 |
| Protein Name | Presenilin-1 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF01080 (Presenilin) |
Summary
- Multi-target molecules 1,936
- Clinical molecules 1
- Avg pChEMBL 7.37
KEGG Pathways (7)
Associated Diseases (4)
Active Molecules (1,936)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
LNWFRQFAJKYOTN
|
8.0 | IC50 | 6 | — | |
XEAMFNQXXHLSLU
|
8.0 | IC50 | 6 | — | |
RCTIQFHQOVGEJY
|
8.0 | IC50 | 6 | — | |
BLJCHCQOTFBOAT
|
8.0 | IC50 | 6 | — | |
CUGYVPGGRCUNPA
|
8.0 | IC50 | 6 | — | |
DGRSGSKYRNNKNH
|
8.0 | IC50 | 6 | — | |
DHCFQUMNNPDWHH
|
8.0 | IC50 | 6 | — | |
DIJHZYZBKQGJCA
|
8.0 | IC50 | 6 | — | |
DUPCKWLECUXWCT
|
8.0 | IC50 | 6 | — | |
LMQTXPPUVFNKBQ
|
8.0 | IC50 | 6 | — | |
PSXOKXJMVRSARX
|
8.0 | IC50 | 6 | — | |
SAJYZUZYZMJMOG
|
8.0 | IC50 | 6 | — | |
SXTJGJFKTKXPMX
|
8.0 | IC50 | 6 | — | |
XQRTXLAOWKZRTD
|
8.0 | IC50 | 6 | — | |
YAYPZOSESAPDFR
|
8.0 | IC50 | 6 | — | |
ZFSWKYURMTXPDV
|
8.0 | IC50 | 6 | — | |
QVNUOJRVQDGJQW
|
7.9 | IC50 | 8 | — | |
XYRXKBBOJKFRBK
|
7.9 | IC50 | 6 | — | |
CHJURRSPZPJQDD
|
7.9 | IC50 | 6 | — | |
CLMFHVQNEUWLFS
|
7.9 | IC50 | 6 | — | |
DDVQYGCPVJHCFB
|
7.9 | IC50 | 6 | — | |
DJWUDIFTUQYCIR
|
7.9 | IC50 | 8 | — | |
GRVMHMVGYPNSMM
|
7.9 | IC50 | 6 | — | |
GXWRGDCHUYWDPZ
|
7.9 | IC50 | 6 | — | |
HBYWQYLFCFDNMA
|
7.9 | IC50 | 6 | — | |
HWKQEZCNMWMGCE
|
7.9 | IC50 | 6 | — | |
IKDPHCOJIWPJEY
|
7.9 | IC50 | 6 | — | |
IWDLRGADTXVFSB
|
7.9 | IC50 | 6 | — | |
IZAOBRWCUGOKNH
|
7.9 | IC50 | 6 | — | |
KZQHKMKBAZNTMD
|
7.9 | IC50 | 6 | — | |
MGFUFELJNJZPQJ
|
7.9 | IC50 | 6 | — | |
OCVSOISGGAYYKC
|
7.9 | IC50 | 6 | — | |
OLOXFVAQGWREAZ
|
7.9 | IC50 | 6 | — | |
VARMHQLFDBTLFX
|
7.9 | IC50 | 6 | — | |
VLVJRTOYCPNRMD
|
7.9 | IC50 | 6 | — | |
DJNHHASAPQZIRO
|
7.9 | IC50 | 6 | — | |
NZXZPEFWHYKCMH
|
7.9 | IC50 | 6 | — | |
RKELUJLKVGWPHP
|
7.9 | IC50 | 6 | — | |
VLJBYLPIUUYIMX
|
7.9 | IC50 | 6 | — | |
WDUWNLHXJVAVNC
|
7.9 | IC50 | 6 | — | |
XPLGLLQQEDYFGW
|
7.9 | IC50 | 6 | — | |
AEHTZESQBYHSRV
|
7.9 | IC50 | 6 | — | |
BIGPVGFXCYBNEC
|
7.9 | IC50 | 6 | — | |
HCHVNBOTRLPDIE
|
7.9 | IC50 | 6 | — | |
IYQPPBLMXJPURV
|
7.9 | IC50 | 6 | — | |
NXPQBVTVDAZRRT
|
7.9 | IC50 | 6 | — | |
OLJWGKMQUSBBIA
|
7.9 | IC50 | 7 | — | |
OLJWGKMQUSBBIA
|
7.9 | IC50 | 2 | — | |
PWWZMSGHCWBIOM
|
7.9 | IC50 | 6 | — | |
SIQJUJBSEDNWPI
|
7.9 | IC50 | 6 | — |