Target Details
UniProt ACP49354
Gene SymbolFNTA
Protein NameProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF01239 (PPTA)
UniProt
Summary
  • Multi-target molecules 1,421
  • Clinical molecules 1125
  • Avg pChEMBL 7.75
KEGG Pathways (1)
Top Co-occurrence Targets
Active Molecules (1,421)
InChIKey pChEMBL Type Targets Clinical
XEWSILGLGYHPRI 8.5 pIC50 3 Yes
LNNRPGCPPFJQSP 8.5 IC50 4 —
YBRQTVAZFOIBMQ 8.5 IC50 2 —
YEEXWMGDSDJZCX 8.5 pIC50 2 Yes
BMOXGURTWHMBKI 8.5 pIC50 2 Yes
BSFBSBUVPRPQFW 8.5 pIC50 2 Yes
DRCFAJOBBUQTRU 8.5 pIC50 2 Yes
DZYGQZQTEVKSFD 8.5 pIC50 2 Yes
FBAPTBLKAIFWHJ 8.5 pIC50 2 Yes
PCMOPVSFMUOUFR 8.5 IC50 2 —
QGCNWBQUPNGUPL 8.5 pIC50 3 Yes
USPFJPDEADLGIG 8.5 pIC50 3 Yes
DFXJFEAHWLUMQK 8.4 IC50 2 —
LMGSQMQVUYDBRD 8.4 pIC50 2 Yes
QWIZYRGWEQXHJG 8.4 pIC50 2 Yes
DWFPFAQHVZRKBX 8.4 pIC50 3 Yes
GQLZRVHYGCXHSR 8.4 IC50 4 —
QHMLQIYABICDHY 8.4 pIC50 2 Yes
RLZPEQLIWYHFHH 8.4 pIC50 3 Yes
TVUZXHJCUAQECC 8.4 pIC50 2 Yes
DAARHFNOAVMALA 8.4 pIC50 2 Yes
YNTPLRZYABBXGF 8.4 pIC50 2 Yes
ZAUBGERWKXAZHI 8.4 pIC50 3 Yes
AOAQWAKHGOYQKE 8.4 pIC50 2 Yes
BOAHFXYLVJDDQK 8.4 pIC50 2 Yes
HAVQZHBSNHGZME 8.4 pIC50 2 Yes
ROPVYNUGSZRGBD 8.4 pIC50 2 Yes
YLWZTUJNSOKAOC 8.4 pIC50 2 Yes
ZDVIZIAAVKFZQO 8.4 IC50 2 —
CYBHYVCTXZJLET 8.4 pIC50 3 Yes
IMLYAVYEFBDHJX 8.4 pIC50 2 Yes
LLCGVIGFFQPTGW 8.4 pIC50 2 Yes
NCOZXTAQUOCINN 8.4 pIC50 3 Yes
PPHNUTLPTANUKD 8.4 pIC50 2 Yes
LUQBIRLUHCYXQM 8.3 pIC50 3 Yes
MHNMEERHZSPWFL 8.3 IC50 3 —
SDWSBMKMILEYGK 8.3 pIC50 2 Yes
CROAYTAFPRXEFL 8.3 pIC50 2 Yes
NXWZJBVSPZNPCA 8.3 pIC50 2 Yes
DHFWHKTUMKQUFQ 8.3 pIC50 2 Yes
BMXLKSIXSXKJGD 8.3 pIC50 2 Yes
FQPVEMPAVWJDIH 8.3 IC50 2 —
HTQHKXXZLMCPEX 8.3 pIC50 2 Yes
HZUKRNKCJCVHQD 8.3 IC50 2 —
KAZRGJXVBVPWLA 8.3 pIC50 2 Yes
WMUCUAKPEIPDIK 8.3 pIC50 2 Yes
LLIPALBHLJKSHD 8.3 pIC50 2 Yes
MXTDFFWHYKUZFS 8.3 pIC50 2 Yes
OBKQMZCTGOCMFK 8.3 IC50 2 —
AAAMHEXGLYVZSJ 8.3 pIC50 2 Yes
2D structure