Target Details
UniProt ACP49354
Gene SymbolFNTA
Protein NameProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF01239 (PPTA)
UniProt
Summary
  • Multi-target molecules 1,421
  • Clinical molecules 1125
  • Avg pChEMBL 7.75
KEGG Pathways (1)
Top Co-occurrence Targets
Active Molecules (1,421)
InChIKey pChEMBL Type Targets Clinical
FRZPVFJBZMEYQN 7.6 pIC50 2 Yes
IBIUCSOTYPMCEO 7.6 pIC50 2 Yes
JXSRHAPARDTOCD 7.6 pIC50 2 Yes
MLRDIJRZSJTOLB 7.6 pIC50 2 Yes
SMFRBSRYCWADEI 7.6 pIC50 2 Yes
BVCQRIMNJALALQ 7.5 pIC50 3 Yes
CPUPJBLXXHGNPV 7.5 pIC50 2 Yes
GILIRUXJPMYMKB 7.5 pIC50 2 Yes
JYNMYKBOYLNHJU 7.5 pIC50 2 Yes
NPDQYTSFLXMUQL 7.5 pIC50 2 Yes
MENPCYFBWXUCAE 7.5 IC50 2 —
PMQORWKGWDLDEI 7.5 pIC50 2 Yes
RARYRWTWIMZZDM 7.5 pIC50 2 Yes
WVXGQIOPZMEAOO 7.5 pIC50 2 Yes
FYTHCBFIMNBITR 7.5 pIC50 2 Yes
KCMSOIVABHUTEI 7.5 IC50 2 —
SQEDCVWGIGZFBX 7.5 pIC50 2 Yes
TYNWPOCZDGESRZ 7.5 IC50 2 —
UOXSWKQZOSEOLM 7.5 pIC50 2 Yes
WINKJJCYTRJCQK 7.5 pIC50 2 Yes
YDXZCFLYIHUBSR 7.5 pIC50 2 Yes
YOZKFSHOKXTDCP 7.5 pIC50 2 Yes
ZOJLZORWIBDCLD 7.5 pIC50 2 Yes
KLEPGMNVHGHALJ 7.5 pIC50 2 Yes
QBXQJODURNKSIQ 7.5 pIC50 2 Yes
UEAFSQXNJOKNMX 7.5 pIC50 2 Yes
WWBMVHKTRROALT 7.5 IC50 2 —
FEGKWAUHIFCFFC 7.5 IC50 2 —
GRSLZTOJSVMRGD 7.5 IC50 2 —
ONWQFUUORXWXJQ 7.5 IC50 2 —
QAJIHSCJMHBCFI 7.5 IC50 2 —
SENXGZXWIWRQSQ 7.5 IC50 2 —
CNHFDLPFXKHRKU 7.5 pIC50 3 Yes
WQCCHVJLXWFMBZ 7.5 pIC50 2 Yes
JOCGRWHRWNIISC 7.5 pIC50 2 Yes
OZONJPYJYNBQFW 7.5 pIC50 2 Yes
OZONJPYJYNBQFW 7.5 IC50 2 —
QRYPFLHPYNVARG 7.5 pIC50 2 Yes
SEZMKJCYZBSCJV 7.5 pIC50 2 Yes
IXEHOZJOSFIOCD 7.5 pIC50 2 Yes
MOCUABRQFZUWQK 7.5 pIC50 2 Yes
ODNODBYULJCPOM 7.5 pIC50 3 Yes
OVQRCNZLFIDOIZ 7.5 pIC50 2 Yes
SDZNMDINWTWWRH 7.5 pIC50 2 Yes
DILCDDZDVRXNSW 7.5 pIC50 2 Yes
JHULRWOTZPYWRZ 7.5 pIC50 2 Yes
QASVCVNBLBRDBC 7.5 pIC50 2 Yes
KDNXAKFCCZIDDV 7.4 pIC50 2 Yes
NVNAHNBLVNBWBA 7.4 pIC50 2 Yes
OFWMOMTWUUKYMP 7.4 pIC50 2 Yes
2D structure