Target Details
UniProt ACP49354
Gene SymbolFNTA
Protein NameProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF01239 (PPTA)
UniProt
Summary
  • Multi-target molecules 1,421
  • Clinical molecules 1125
  • Avg pChEMBL 7.75
KEGG Pathways (1)
Top Co-occurrence Targets
Active Molecules (1,421)
InChIKey pChEMBL Type Targets Clinical
RXNSVMOCVKTVBN 7.7 pIC50 2 Yes
SFKOTJCSIYBZQW 7.7 pIC50 3 Yes
UMMFUJAKLTXUKT 7.7 pIC50 2 Yes
WBAITUPEPUOTGJ 7.7 pIC50 2 Yes
WSTHABWJAPYXLV 7.7 pIC50 2 Yes
XZAROMHMWKRDFK 7.7 pIC50 2 Yes
YOSWFXLZVOUMIC 7.7 pIC50 3 Yes
GAJLKAVQYXFCRU 7.7 IC50 2 —
HVZJXDZOBBNWBN 7.7 pIC50 2 Yes
JATLZNPDYCNKTL 7.7 pIC50 3 Yes
KXTGYMBIVOYPPF 7.7 pIC50 2 Yes
MRONYHYWJWVKKK 7.7 pIC50 2 Yes
QQZYKSKGVSDVOW 7.7 IC50 2 Yes
QVELSCNTBHCXNR 7.7 pIC50 2 Yes
ASGRMKOMFCIGQU 7.7 pIC50 2 Yes
FQPSHGVXEHSFQP 7.7 pIC50 2 Yes
NOECLYKTPGJCOD 7.7 pIC50 2 Yes
PKJPNZQYQXQHRH 7.7 pIC50 2 Yes
QAIUZYFKQAGOBZ 7.7 pIC50 3 Yes
XSJWOMAHMIQEAO 7.7 IC50 2 —
FEVHHJGFOBPUMV 7.6 IC50 2 —
HHCUIUUICDIYLM 7.6 IC50 2 —
HHCUIUUICDIYLM 7.6 pIC50 2 Yes
HVDZPMNIJYLAIO 7.6 pIC50 2 Yes
JUHFBGZNDZFVMC 7.6 pIC50 2 Yes
OJUQOLIQROCOEZ 7.6 pIC50 2 Yes
UOZSXSDLAGEQQS 7.6 IC50 2 —
WDHZBVVWQWCYIS 7.6 pIC50 2 Yes
KRVAMXVIPMAUPF 7.6 pIC50 2 Yes
FCAIKTYDWLTVQR 7.6 pIC50 2 Yes
UEBNHTSMTQUOQB 7.6 IC50 2 —
XNUGRKDPRCDTJX 7.6 pIC50 2 Yes
YBROKHNFEQXGSA 7.6 pIC50 2 Yes
CSJCILYSGLDOHR 7.6 pIC50 2 Yes
IIPCWBJMJZVLOK 7.6 IC50 3 —
KMDYZZOYCZPGES 7.6 IC50 2 —
KMNYYAJYASNHCC 7.6 IC50 3 —
MVPXMHNFAQUXRM 7.6 IC50 2 —
SDOSQMQIXOUHSQ 7.6 pIC50 2 Yes
UHGZCRVPTZSYOB 7.6 pIC50 2 Yes
UMLXJXCOOBRTMY 7.6 pIC50 2 Yes
WOMLPRIYJFYGGD 7.6 pIC50 2 Yes
CSHPNTOXXBGLLQ 7.6 pIC50 2 Yes
GVGGCDOKAJYANR 7.6 pIC50 2 Yes
HBICQBWDOZPTLD 7.6 pIC50 2 Yes
JQFVATYKOSELCB 7.6 pIC50 2 Yes
VNGJGARSHMJYAY 7.6 pIC50 2 Yes
VXXYAJGHLFTFPE 7.6 pIC50 2 Yes
BYWFNZWJIKYEJQ 7.6 pIC50 3 Yes
DIEDXRCNBQHMSM 7.6 IC50 2 —
2D structure