Target Details
UniProt ACP49354
Gene SymbolFNTA
Protein NameProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF01239 (PPTA)
UniProt
Summary
  • Multi-target molecules 1,421
  • Clinical molecules 1125
  • Avg pChEMBL 7.75
KEGG Pathways (1)
Top Co-occurrence Targets
Active Molecules (1,421)
InChIKey pChEMBL Type Targets Clinical
QAJIHSCJMHBCFI 7.8 pIC50 3 Yes
QAQOQARNGPJYIW 7.8 IC50 2 —
QMJPRCONYFSJIH 7.8 IC50 2 —
SGTLQNSIWNWVHS 7.8 pIC50 2 Yes
UMMFUJAKLTXUKT 7.8 pIC50 3 Yes
VDBMNWLQVQBYJK 7.8 pIC50 2 Yes
XHJYBXKCAUZIFW 7.8 pIC50 2 Yes
YEKVAAWBCICTOR 7.8 pIC50 2 Yes
JOCGRWHRWNIISC 7.8 pIC50 2 Yes
CXDHLMPYQMURSA 7.8 IC50 2 —
CXLOTEIXOSAUFS 7.8 pIC50 2 Yes
DEDIUQJQNGGRTH 7.8 pIC50 2 Yes
DPYSMSBXSGBPHE 7.8 pIC50 2 Yes
FFNXZDBGNUKYOO 7.8 pIC50 2 Yes
FQWLXKORHCUAJF 7.8 pIC50 2 Yes
HSDDYEHCQJJYDT 7.8 pIC50 2 Yes
IVHZRYBZVXHBJC 7.8 pIC50 3 Yes
NIOSFAVPXNLLPG 7.8 pIC50 2 Yes
NJRTXLQMEKTXLZ 7.8 pIC50 3 Yes
ULZTVJKTSYZRPI 7.8 IC50 2 —
XZTNIAUKBZXXOI 7.8 pIC50 2 Yes
YRERXVCECMZRBL 7.8 pIC50 2 Yes
MOEKWEOHPBQAGQ 7.8 IC50 2 —
FNUXYNKOUPKEGG 7.8 IC50 2 —
IXYYNWLSRODQGM 7.8 IC50 2 —
ZWHQLAPMFTYJKB 7.8 IC50 2 —
DHAAFTKZGRVWHT 7.7 pIC50 2 Yes
PMCYJSRQOFQRLF 7.7 pIC50 3 Yes
SLYBJCUKCICSBD 7.7 pIC50 4 Yes
SSYAXKLPIZZQEY 7.7 pIC50 2 Yes
UMMFUJAKLTXUKT 7.7 pIC50 3 Yes
USLBJXXUUBLNQX 7.7 pIC50 2 Yes
RBZQXEMPWMGPEK 7.7 IC50 3 —
DZJIZUHWPKFMQZ 7.7 IC50 2 —
DZJIZUHWPKFMQZ 7.7 pIC50 2 Yes
FBTSVHIGWRLBOS 7.7 pIC50 3 Yes
IQBYTJXPJBQWHC 7.7 pIC50 2 Yes
OWLHHDOYDDOMTE 7.7 pIC50 2 Yes
PPXJVZJWVHFFJW 7.7 pIC50 2 Yes
VMPOGPLMXVTSIM 7.7 pIC50 2 Yes
XCXMUQZTMJHHML 7.7 pIC50 2 Yes
XYHRDQOAIUJLAB 7.7 pIC50 2 Yes
DRHSBBXCFYHMCC 7.7 pIC50 2 Yes
KVWMCWMRPHPVTC 7.7 pIC50 2 Yes
LEOFHPLVHZUFJS 7.7 pIC50 3 Yes
LMBPTRXCFXWLRW 7.7 pIC50 2 Yes
LMTIEVNRUFAFPM 7.7 IC50 2 —
ODRIJWKMQUKGQK 7.7 pIC50 2 Yes
OPSSECGRIFWABR 7.7 pIC50 2 Yes
PVWYVGHJHHUPFS 7.7 pIC50 2 Yes
2D structure