Target Details
UniProt ACP49354
Gene SymbolFNTA
Protein NameProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF01239 (PPTA)
UniProt
Summary
  • Multi-target molecules 1,421
  • Clinical molecules 1125
  • Avg pChEMBL 7.75
KEGG Pathways (1)
Top Co-occurrence Targets
Active Molecules (1,421)
InChIKey pChEMBL Type Targets Clinical
WEYQMQWSOGQRDE 8.0 pIC50 2 Yes
ZARKMBOXAZGLSX 8.0 pIC50 2 Yes
BLFLJMSPCIGQQF 7.9 pIC50 2 Yes
BMGIODYUKGDYTO 7.9 pIC50 3 Yes
CXHRDHMBLZINQP 7.9 pIC50 2 Yes
KBXDQFQFFRYOJS 7.9 pIC50 2 Yes
KNCKGFQSMLPZLS 7.9 IC50 2 —
OBVKAVIOGZYQPA 7.9 pIC50 2 Yes
PMOBHNORZCLDTE 7.9 pIC50 2 Yes
QBIOEIXFXALQMC 7.9 pIC50 2 Yes
QXMRHTKQHROEFK 7.9 pIC50 2 Yes
VCIMPMYMNFFUID 7.9 pIC50 2 Yes
VTPCNRSHUJQADS 7.9 pIC50 3 Yes
YVPYFTVDDPMUSO 7.9 pIC50 2 Yes
YZFYPECRJZGSGJ 7.9 IC50 2 —
DPKDWERTWMZACY 7.9 pIC50 2 Yes
MHNMEERHZSPWFL 7.9 IC50 3 —
MNQQHQBXRZHHJO 7.9 IC50 2 —
NMPOEHMYTSFAOT 7.9 pIC50 3 Yes
ROFGUUIGELBBOO 7.9 pIC50 2 Yes
SQSRCLAOTRHUQX 7.9 pIC50 3 Yes
UJADEKDYGZTGTF 7.9 IC50 2 —
VSZUAPYSZPDEHJ 7.9 IC50 2 —
WBCNUAHNRQZIKX 7.9 pIC50 2 Yes
XMTFJKKQVGPEBU 7.9 pIC50 2 Yes
RBZQXEMPWMGPEK 7.9 IC50 3 —
AQAZIJJBKQIIAP 7.8 pIC50 3 Yes
FSPDQNXKMXHLSM 7.8 pIC50 2 Yes
PMPOWTYDGGSMHD 7.8 pIC50 2 Yes
QIVUVRPLLRMTDC 7.8 pIC50 2 Yes
SCUYGSDJSUFKNT 7.8 pIC50 2 Yes
UJRNHAPUICJBGE 7.8 pIC50 2 Yes
UZOLOYJCNMNVOM 7.8 pIC50 2 Yes
VHFURXMPOXMFQR 7.8 pIC50 2 Yes
YPOHNWIPWIEUFZ 7.8 pIC50 2 Yes
IOTPEJFSRLIAMG 7.8 pIC50 2 Yes
IZVROLMEXNRNHZ 7.8 pIC50 4 Yes
JHMVRJULHPLSFV 7.8 pIC50 2 Yes
JQDSCDOLMRCKLS 7.8 pIC50 2 Yes
LZUIFBUKSHGFTB 7.8 pIC50 2 Yes
MIUVLTBXZYHORO 7.8 pIC50 2 Yes
MSYWKAUBOIFIPF 7.8 pIC50 2 Yes
QRWXUOIBXUCQKJ 7.8 IC50 2 —
UQRQADYTKHCQGV 7.8 pIC50 2 Yes
WBKRBGCANDALOX 7.8 pIC50 2 Yes
ZXRLFIJLBNQELO 7.8 pIC50 2 Yes
DSUYZKFAJRJFFP 7.8 IC50 2 —
FRGOPLSOHOTEEH 7.8 pIC50 2 Yes
JNXBREYWTYTYFQ 7.8 IC50 2 —
OLCYWDOABCSFNC 7.8 pIC50 2 Yes
2D structure