Target Details
| UniProt AC | P49354 |
|---|---|
| Gene Symbol | FNTA |
| Protein Name | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF01239 (PPTA) |
Summary
- Multi-target molecules 1,421
- Clinical molecules 1125
- Avg pChEMBL 7.75
KEGG Pathways (1)
Active Molecules (1,421)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
ZSITWYGPKGRMKP
|
11.0 | pIC50 | 2 | Yes | |
DGTSSSGHGKXRIS
|
10.5 | pIC50 | 2 | Yes | |
QORHMONMEQMITC
|
10.4 | pIC50 | 2 | Yes | |
BDXLTTUQHGMFEE
|
10.2 | pIC50 | 3 | Yes | |
BILZFSWHUDZYHD
|
10.2 | IC50 | 2 | — | |
MHNMEERHZSPWFL
|
10.2 | pIC50 | 3 | Yes | |
MHNMEERHZSPWFL
|
10.2 | pIC50 | 3 | Yes | |
OMQYMCBJBYJVGL
|
10.1 | pIC50 | 2 | Yes | |
PUBWKJYHDRHOJR
|
10.1 | pIC50 | 2 | Yes | |
QRBLNORQTYKILD
|
10.1 | pIC50 | 2 | Yes | |
AEUOJCZWQRBEMN
|
10.0 | pIC50 | 3 | Yes | |
HDGVZUWMGHDPLU
|
10.0 | pIC50 | 2 | Yes | |
HGGZKXBVGGKUJC
|
10.0 | IC50 | 2 | — | |
HQRMLYBYQCBWRT
|
10.0 | IC50 | 2 | — | |
NLKNPWNNYCYNKB
|
10.0 | pIC50 | 3 | Yes | |
QMIGNVNXSVGBEL
|
10.0 | pIC50 | 2 | Yes | |
QYLBZDCYGRTUQE
|
10.0 | pIC50 | 2 | Yes | |
RRLPKUJYAGTYEF
|
10.0 | pIC50 | 2 | Yes | |
XWZNGPIAPMKVOC
|
10.0 | pIC50 | 2 | Yes | |
NUJGHNLMPMXIMK
|
10.0 | pIC50 | 2 | Yes | |
SJZGJLYNRZRTHV
|
9.9 | pIC50 | 2 | Yes | |
VBWSBMOTOPMPHQ
|
9.9 | pIC50 | 2 | Yes | |
WKHUKTIZMOPZJE
|
9.9 | pIC50 | 3 | Yes | |
WQPYGRKAOXZYEH
|
9.9 | pIC50 | 2 | Yes | |
RORDRPRBYLMVPE
|
9.9 | pIC50 | 2 | Yes | |
RZBJVSPOAOKUHC
|
9.9 | pIC50 | 2 | Yes | |
QQZYKSKGVSDVOW
|
9.8 | pIC50 | 2 | Yes | |
DFXJFEAHWLUMQK
|
9.8 | IC50 | 3 | — | |
MLBHNPAXTLCWTO
|
9.8 | pIC50 | 2 | Yes | |
VDOIRLNHAAJVAF
|
9.8 | pIC50 | 2 | Yes | |
VUSLWIIXXJGJJI
|
9.8 | pIC50 | 2 | Yes | |
IOTNSECWYWCDGM
|
9.8 | pIC50 | 2 | Yes | |
WARZQQRPINBDAJ
|
9.8 | pIC50 | 3 | Yes | |
WWGONUOHFVVGEW
|
9.8 | pIC50 | 2 | Yes | |
FTAHDFVHYRVMMM
|
9.7 | pIC50 | 2 | Yes | |
KVTUJRZUQCULNT
|
9.7 | pIC50 | 3 | Yes | |
CPCCCCDBCSOFNS
|
9.7 | pIC50 | 3 | Yes | |
DQULASPPLJLHJJ
|
9.7 | pIC50 | 2 | Yes | |
OBXLXUGOZZWQOW
|
9.7 | pIC50 | 4 | Yes | |
ZFBGYVVVVKZTFW
|
9.7 | pIC50 | 3 | Yes | |
ANJRETXSJRSEAS
|
9.7 | pIC50 | 2 | Yes | |
VKJRLKJFWHHKFZ
|
9.7 | pIC50 | 2 | Yes | |
VQNYIQPZXRNJMG
|
9.7 | pIC50 | 3 | Yes | |
YYDYJITZGLMMFM
|
9.7 | IC50 | 2 | — | |
FOAZKKVMCXADMU
|
9.7 | pIC50 | 2 | Yes | |
JGRNPBJNNBQZGQ
|
9.7 | pIC50 | 2 | Yes | |
KTIYPXIOLFUYRZ
|
9.6 | pIC50 | 2 | Yes | |
MXROXRMSFVHUHH
|
9.6 | pIC50 | 3 | Yes | |
LOJYBMUXZXMFRE
|
9.6 | pIC50 | 2 | Yes | |
DOZZPCQVJJBKME
|
9.6 | pIC50 | 3 | Yes |