TDO2 — MultiTargetDB

Target Details

UniProt AC	`P48775`
Gene Symbol	TDO2
Protein Name	Tryptophan 2,3-dioxygenase
Organism	Homo sapiens
Entry Name
Organism Category	Human
Pfam Domains	PF03301 (Trp_dioxygenase)

Summary

Multi-target molecules 240
Clinical molecules 0
Avg pChEMBL 6.59

KEGG Pathways (3)

Associated Diseases (1)

Hypertryptophanemia

Top Co-occurrence Targets

IDO1 240 shared
CYP3A4 4 shared
IDO2 2 shared
CYP2C9 2 shared
srtA 1 shared
SIGMAR1 1 shared
SENP8 1 shared
CYP1B1 1 shared
PPARA 1 shared
PTGS2 1 shared

Active Molecules (240)

InChIKey	pChEMBL	Type	Targets	Clinical
`XOIBIBZONGFJRB`	6.2	IC50	2	—
`CXWRSQDVQMEABQ`	6.2	IC50	2	—
`GPFCJWJSFAPBNK`	6.2	IC50	2	—
`JJPOOSLOAJIUFW`	6.2	IC50	2	—
`WKDBQKZUIUUMLE`	6.2	IC50	2	—
`AEMVYCHLYDWVGY`	6.2	IC50	2	—
`FHLMOHXPRRSHRY`	6.2	IC50	2	—
`JUXORWMABIQBQK`	6.2	IC50	2	—
`WOALNEUXJJGUMC`	6.2	IC50	2	—
`WUQOZYPTLRTOED`	6.2	IC50	2	—
`FUGHJGNJPYRQFX`	6.2	IC50	2	—
`HNMLFYAVNXUMDX`	6.2	IC50	2	—
`YPWFUCJPQCIMOV`	6.2	IC50	2	—
`QUDANWQDAHSKPJ`	6.2	IC50	2	—
`YOTSKOBPSGTBDN`	6.2	IC50	2	—
`OJBKRVHPGUIOAM`	6.2	IC50	2	—
`RVSUFTQTIGUXBU`	6.2	IC50	2	—
`VZSQBPCMUNWVCP`	6.2	IC50	2	—
`PVVXYQFKBXRDSW`	6.2	IC50	2	—
`AZXIIVGCMUUVTL`	6.1	IC50	2	—
`CICLBCJHLAGMIY`	6.1	IC50	2	—
`OGJIUQZGECSYFP`	6.1	IC50	2	—
`UUSLIOFTAIOJSB`	6.1	IC50	2	—
`AQVLIGKLPHQUOG`	6.1	IC50	2	—
`GILHXZMMODSEGS`	6.1	IC50	2	—
`ZDRWYPMDHVEHIG`	6.1	IC50	2	—
`IBWLZSJWENDWOJ`	6.1	IC50	2	—
`KHONZILMMZKIQL`	6.1	IC50	2	—
`LQPZZJZECDWKCW`	6.1	IC50	2	—
`NRSXRBWOTJJSBQ`	6.1	IC50	2	—
`KXWJQTZVXMANSZ`	6.0	IC50	2	—
`VSNYUPBGAQQVCB`	6.0	IC50	2	—
`CCUBFPOONNDKHL`	6.0	IC50	2	—
`MGMLZAGUHKYFRS`	6.0	IC50	2	—
`OFZXVDIQPLYNJJ`	6.0	IC50	2	—
`QTUSOWIRENUFCA`	6.0	IC50	2	—
`FPKOOQWQTIMSGB`	6.0	IC50	2	—
`HUXJWSCWWJDQNA`	6.0	IC50	2	—
`KQBLDQUVTHHHOZ`	6.0	IC50	2	—
`NUOMVFPVKSHIDX`	6.0	IC50	2	—