Target Details
| UniProt AC | P48061 |
|---|---|
| Gene Symbol | CXCL12 |
| Protein Name | Stromal cell-derived factor 1 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00048 (IL8) |
Summary
- Multi-target molecules 4
- Clinical molecules 0
- Avg pChEMBL 6.88
KEGG Pathways (11)
- Axon guidance
- Chemokine signaling pathway
- Cytokine-cytokine receptor interaction
- Human cytomegalovirus infection
- Intestinal immune network for IgA production
- Leukocyte transendothelial migration
- NF-kappa B signaling pathway
- Pathways in cancer
- Regulation of actin cytoskeleton
- Rheumatoid arthritis
- Viral protein interaction with cytokine and cytokine receptor
Associated Diseases (1)
Active Molecules (4)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
KCTNGNPVURILGU
|
7.3 | Ki | 2 | — | |
YIQPUIGJQJDJOS
|
7.2 | IC50 | 5 | — | |
YIXBFJMCXWGURC
|
6.8 | Kd | 2 | — | |
HAKFGEFAVSVPJO
|
6.2 | IC50 | 2 | — |