Target Details
| UniProt AC | P48058 |
|---|---|
| Gene Symbol | GRIA4 |
| Protein Name | Glutamate receptor 4 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF01094 (ANF_receptor) PF00060 (Lig_chan) PF10613 (Lig_chan-Glu_bd) |
Summary
- Multi-target molecules 103
- Clinical molecules 0
- Avg pChEMBL 6.85
KEGG Pathways (11)
- Amphetamine addiction
- Circadian entrainment
- Dopaminergic synapse
- Glutamatergic synapse
- Huntington disease
- Neuroactive ligand signaling
- Neuroactive ligand-receptor interaction
- Nicotine addiction
- Pathways of neurodegeneration - multiple diseases
- Retrograde endocannabinoid signaling
- cAMP signaling pathway
Associated Diseases (2)
Active Molecules (103)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
LPMRCCNDNGONCD
|
6.0 | IC50 | 11 | — | |
ROBLGUMDXHEHOO
|
6.0 | Ki | 4 | — | |
VIROLUKPVOVJDX
|
6.0 | Ki | 4 | — |