Target Details
| UniProt AC | P46109 |
|---|---|
| Gene Symbol | CRKL |
| Protein Name | Crk-like protein |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00017 (SH2) PF00018 (SH3_1) PF07653 (SH3_2) |
Summary
- Multi-target molecules 1
- Clinical molecules 0
- Avg pChEMBL 7.11
KEGG Pathways (20)
- Bacterial invasion of epithelial cells
- Chemokine signaling pathway
- Chronic myeloid leukemia
- Efferocytosis
- ErbB signaling pathway
- Fc gamma R-mediated phagocytosis
- Focal adhesion
- Growth hormone synthesis, secretion and action
- Human cytomegalovirus infection
- Human immunodeficiency virus 1 infection
- Insulin signaling pathway
- MAPK signaling pathway
- MicroRNAs in cancer
- Neurotrophin signaling pathway
- Pathways in cancer
- Rap1 signaling pathway
- Regulation of actin cytoskeleton
- Renal cell carcinoma
- Shigellosis
- Yersinia infection
Active Molecules (1)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
ZCCPLJOKGAACRT
|
7.1 | Kd | 599 | — |