Target Details
| UniProt AC | P42261 |
|---|---|
| Gene Symbol | GRIA1 |
| Protein Name | Glutamate receptor 1 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF01094 (ANF_receptor) PF00060 (Lig_chan) PF10613 (Lig_chan-Glu_bd) |
Summary
- Multi-target molecules 143
- Clinical molecules 0
- Avg pChEMBL 7.18
KEGG Pathways (15)
- Amphetamine addiction
- Amyotrophic lateral sclerosis
- Circadian entrainment
- Dopaminergic synapse
- Glutamatergic synapse
- Huntington disease
- Long-term depression
- Long-term potentiation
- Neuroactive ligand signaling
- Neuroactive ligand-receptor interaction
- Nicotine addiction
- Pathways of neurodegeneration - multiple diseases
- Retrograde endocannabinoid signaling
- Spinocerebellar ataxia
- cAMP signaling pathway
Associated Diseases (2)