Target Details
| UniProt AC | P36896 |
|---|---|
| Gene Symbol | ACVR1B |
| Protein Name | Activin receptor type-1B |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF01064 (Activin_recp) PF00069 (Pkinase) PF08515 (TGF_beta_GS) |
Summary
- Multi-target molecules 107
- Clinical molecules 10
- Avg pChEMBL 7.07
KEGG Pathways (3)
Associated Diseases (1)
Active Molecules (107)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
AQSSMEORRLJZLU
|
9.0 | Kd | 34 | Yes | |
FHTCHCUICJOIGJ
|
8.7 | IC50 | 7 | — | |
NLTJLIGESBNQSN
|
8.6 | IC50 | 2 | — | |
CKODUGCWZCWIRZ
|
8.4 | IC50 | 2 | — | |
JJYZCPRITYKJAQ
|
8.4 | IC50 | 2 | — | |
NRALVILIKBNNQX
|
8.4 | IC50 | 2 | — | |
YGLGBLUEVWJWHB
|
8.4 | IC50 | 2 | — | |
HXHAJRMTJXHJJZ
|
8.4 | Kd | 52 | Yes | |
YOKGFEAEVZNOAR
|
8.3 | IC50 | 5 | — | |
WQPRHDZTTYJDPW
|
8.3 | IC50 | 2 | — | |
POMBIFQUJUHXAV
|
8.1 | IC50 | 2 | — | |
GUBJNPWVIUFSTR
|
8.0 | Kd | 103 | — | |
IVGZZSIANNYXTI
|
8.0 | IC50 | 2 | — | |
OCJCDFHRNVHPGQ
|
8.0 | IC50 | 2 | — | |
NUVPAWNZKYSCFY
|
8.0 | IC50 | 2 | — | |
OIYYETCFCIAZSC
|
8.0 | IC50 | 2 | — | |
WETVZDDFVHQTTQ
|
7.9 | IC50 | 2 | — | |
YJKNBYBEJYUUHW
|
7.9 | IC50 | 2 | — | |
FJCDSQATIJKQKA
|
7.9 | IC50 | 5 | — | |
ODWRQIDMGOOEIE
|
7.9 | IC50 | 2 | — | |
POPIUCWMQJYOGO
|
7.9 | IC50 | 2 | — | |
RIWTUJFFSTVYPW
|
7.9 | IC50 | 6 | — | |
QPFVXQGTWSDAJK
|
7.8 | IC50 | 3 | — | |
RYKSGWSKILPDDY
|
7.6 | IC50 | 4 | — | |
JCBZLQOFQWJOBF
|
7.6 | IC50 | 2 | — | |
PVBJXPIQVPYBQR
|
7.6 | IC50 | 2 | — | |
NVZWXPUBNZUNFM
|
7.6 | IC50 | 2 | — | |
MQFUFNHTCJRLKW
|
7.6 | IC50 | 6 | — | |
MWKSRKSEWLRPBL
|
7.6 | Kd | 1075 | — | |
FFLJVBPCONQSQW
|
7.6 | IC50 | 8 | — | |
HPZDDBNHJHAGNV
|
7.5 | IC50 | 2 | — | |
WJASKODGMHBDFO
|
7.5 | IC50 | 5 | — | |
LUJQZBILMIUCPF
|
7.5 | IC50 | 2 | — | |
JZVPITOQWJPGIA
|
7.5 | IC50 | 2 | — | |
OAYQAXXBPMOPLN
|
7.5 | IC50 | 2 | — | |
UXFTVPGMWIESDP
|
7.5 | IC50 | 2 | — | |
NRNOAZUAWDMPFI
|
7.4 | IC50 | 2 | — | |
QGMSQMSDEUEWCM
|
7.4 | IC50 | 2 | — | |
GVDHTILDVBEBLW
|
7.4 | IC50 | 2 | — | |
ZJRZWWGSQJZWFS
|
7.3 | IC50 | 2 | — | |
VYTQMUCONGRNBX
|
7.3 | IC50 | 3 | — | |
IPBLCOKXDQHSQW
|
7.2 | IC50 | 2 | — | |
MFAQYJIYDMLAIM
|
7.2 | Kd | 130 | Yes | |
OWIYYKSTVQMPLM
|
7.2 | IC50 | 2 | — | |
WGZOTBUYUFBEPZ
|
7.2 | IC50 | 4 | — | |
ZCCPLJOKGAACRT
|
7.1 | Kd | 599 | — | |
UIARLYUEJFELEN
|
7.1 | Kd | 289 | Yes | |
OGPVQKHTKOAKDQ
|
7.1 | IC50 | 2 | — | |
FDMRIXRWLAMVEF
|
7.0 | IC50 | 2 | — | |
VAARYSWULJUGST
|
7.0 | Kd | 119 | Yes |