Target Details
| UniProt AC | P36402 |
|---|---|
| Gene Symbol | TCF7 |
| Protein Name | Transcription factor 7 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF08347 (CTNNB1_binding) PF00505 (HMG_box) |
Summary
- Multi-target molecules 2
- Clinical molecules 0
- Avg pChEMBL 6.28
KEGG Pathways (22)
- Acute myeloid leukemia
- Adherens junction
- Alcoholic liver disease
- Arrhythmogenic right ventricular cardiomyopathy
- Basal cell carcinoma
- Breast cancer
- Cadherin signaling
- Colorectal cancer
- Cushing syndrome
- Endometrial cancer
- Gastric cancer
- Hepatocellular carcinoma
- Hippo signaling pathway
- Human papillomavirus infection
- Kaposi sarcoma-associated herpesvirus infection
- Melanogenesis
- Pathways in cancer
- Prostate cancer
- Salmonella infection
- Signaling pathways regulating pluripotency of stem cells
- Thyroid cancer
- Wnt signaling pathway
Active Molecules (2)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
GFKMAMBPWANCBQ
|
6.4 | Ki | 2 | — | |
OQIIPRFMLCIWTR
|
6.2 | Ki | 3 | — |