Target Details
| UniProt AC | P35498 |
|---|---|
| Gene Symbol | SCN1A |
| Protein Name | Sodium channel protein type 1 subunit alpha |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00520 (Ion_trans) PF24609 (IQ_SCN5A_C) PF06512 (Na_trans_assoc) PF11933 (Na_trans_cytopl) |
Summary
- Multi-target molecules 542
- Clinical molecules 4
- Avg pChEMBL 7.76
KEGG Pathways (1)
Associated Diseases (6)
Active Molecules (542)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
DJWPADYZPFIDJN
|
9.5 | IC50 | 2 | — | |
ZAVPMEKMFCMVLI
|
9.1 | IC50 | 2 | — | |
QEKXZOFUTIHYII
|
8.9 | IC50 | 2 | — | |
QYRGQKYFSMLZTB
|
8.8 | IC50 | 2 | — | |
BNHLIATWSNXZTC
|
8.8 | IC50 | 2 | — | |
QMIHBNPMTMLUMI
|
8.8 | IC50 | 3 | — | |
QQRDUMOOLIZBOV
|
8.8 | IC50 | 2 | — | |
ZYWBKPBGYHQNDP
|
8.8 | IC50 | 2 | — | |
KWAURGCHFYCYPQ
|
8.8 | IC50 | 4 | — | |
LJDHLZQUJUBCSY
|
8.8 | IC50 | 2 | — | |
QMIHBNPMTMLUMI
|
8.8 | IC50 | 2 | — | |
CZPZFJNHIHVBHS
|
8.7 | IC50 | 2 | — | |
HPKDBJLYPHESDH
|
8.7 | IC50 | 2 | — | |
KRXDZKXQDVLVEO
|
8.7 | IC50 | 2 | — | |
PPNSUOZZLIDACH
|
8.7 | IC50 | 2 | — | |
REXMKIZHPWCXDF
|
8.7 | IC50 | 2 | — | |
XLXIPEOIRIBHSV
|
8.7 | IC50 | 2 | — | |
AMNOVZQLFQDFAJ
|
8.7 | IC50 | 2 | — | |
CYZIUYSSULFUGZ
|
8.7 | IC50 | 2 | — | |
GEVQKHWJSOLJFV
|
8.7 | IC50 | 2 | — | |
RCSJQJZNZNGWGY
|
8.7 | IC50 | 2 | — | |
JDOPSZPOSAPHFB
|
8.7 | IC50 | 2 | — | |
PIOVISPQQWESRU
|
8.7 | IC50 | 2 | — | |
WKRWUEJFYAVPIB
|
8.7 | IC50 | 2 | — | |
YLTIDMONXBEYJP
|
8.7 | IC50 | 2 | — | |
ZWFDZIUIRJDLRG
|
8.7 | IC50 | 2 | — | |
BVXDDXBPDJMLDH
|
8.7 | IC50 | 2 | — | |
OZAYOHJGXLWETR
|
8.7 | IC50 | 2 | — | |
WBUKUXXILSESLB
|
8.7 | IC50 | 3 | — | |
XXYUPEAYWNMJAB
|
8.7 | IC50 | 2 | — | |
CIXVIWMKNATLIZ
|
8.6 | IC50 | 2 | — | |
MARFCZKCASKJQG
|
8.6 | IC50 | 2 | — | |
RPQXVSUAYFXFJA
|
8.6 | IC50 | 8 | — | |
SDFWLGIHLRLHLP
|
8.6 | IC50 | 3 | — | |
WGJKXBIAQQOYRR
|
8.6 | IC50 | 2 | — | |
CYZIUYSSULFUGZ
|
8.6 | IC50 | 2 | — | |
KRXDZKXQDVLVEO
|
8.6 | IC50 | 2 | — | |
LXLJQUXLUKXWCO
|
8.6 | IC50 | 2 | — | |
YRRNEWYACBDUSW
|
8.6 | IC50 | 2 | — | |
CZPZFJNHIHVBHS
|
8.6 | IC50 | 2 | — | |
IPZMXZLTFKXKRB
|
8.6 | IC50 | 2 | — | |
MTNCDKKFVRLAMN
|
8.6 | IC50 | 2 | — | |
PRCIGHMFXRYAIG
|
8.6 | IC50 | 2 | — | |
XZGCZUMRJHFZPF
|
8.6 | IC50 | 2 | — | |
AGUMLPYUAXPZOR
|
8.6 | IC50 | 2 | — | |
BSUOGRFZEVVVBR
|
8.6 | IC50 | 2 | — | |
VTXDKIKWVYIKOF
|
8.6 | IC50 | 2 | — | |
CIXVIWMKNATLIZ
|
8.6 | IC50 | 3 | — | |
CYZIUYSSULFUGZ
|
8.6 | IC50 | 2 | — | |
DBQDFEJHUOPISY
|
8.6 | IC50 | 2 | — |