Target Details
| UniProt AC | P34913 |
|---|---|
| Gene Symbol | EPHX2 |
| Protein Name | Bifunctional epoxide hydrolase 2 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00561 (Abhydrolase_1) PF00702 (Hydrolase) |
Summary
- Multi-target molecules 257
- Clinical molecules 2
- Avg pChEMBL 8.15
KEGG Pathways (6)
Associated Diseases (1)
Active Molecules (257)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
BLOKHJPAYORLMS
|
10.3 | Ki | 2 | — | |
LHRXHTKENPCGSZ
|
10.2 | Ki | 2 | — | |
RMXODCJBXSHGRQ
|
10.1 | Ki | 2 | — | |
XSHFQIYGMXETOA
|
9.8 | Ki | 2 | — | |
GEPCEEXLBUBPNZ
|
9.6 | Ki | 2 | — | |
KCYFENQWYLTXQO
|
9.5 | Ki | 2 | — | |
HGZXFZJCBJNICS
|
9.5 | Ki | 2 | — | |
JZMJFVHUWVWIOY
|
9.4 | Ki | 2 | — | |
IIGBRXYVEOEPDV
|
9.4 | Ki | 2 | — | |
XLMFYLPQZAFJLS
|
9.4 | Ki | 2 | — | |
CLIYCAVTAMNXLB
|
9.4 | IC50 | 2 | — | |
FSULYXCULMDLOG
|
9.4 | IC50 | 2 | — | |
HAMLMZMEEHRTDE
|
9.4 | IC50 | 2 | — | |
LJRCVVXGTSHEFM
|
9.4 | IC50 | 2 | — | |
RFONAXXDMGITIV
|
9.4 | IC50 | 2 | — | |
VPHLBLQNXMWQOL
|
9.4 | IC50 | 3 | — | |
WTPMKFXZAUAECV
|
9.4 | IC50 | 3 | — | |
MUXBEWJOYODXBO
|
9.3 | Ki | 2 | — | |
DRRLHDVXGXINDY
|
9.3 | IC50 | 2 | — | |
FNHKPVJBJVTLMP
|
9.3 | IC50 | 29 | — | |
GKESASBPGZTTKO
|
9.3 | Ki | 2 | — | |
JNPWHXLRBKEIPP
|
9.3 | IC50 | 3 | — | |
OUNLWXRDCKWIDY
|
9.3 | IC50 | 2 | — | |
QSSFQCIDYRJNEF
|
9.3 | IC50 | 2 | — | |
VZOUKWZMPPMODY
|
9.3 | IC50 | 3 | — | |
VZOUKWZMPPMODY
|
9.3 | IC50 | 3 | — | |
XMHPFTJYRYODSK
|
9.3 | IC50 | 2 | — | |
XVUHBENWLBKIMX
|
9.3 | IC50 | 2 | — | |
XVVKIKYRNROXOE
|
9.3 | Ki | 2 | — | |
GHAZMUIBGZEWFT
|
9.3 | IC50 | 4 | — | |
UMAOSXFOMFFLAU
|
9.3 | Ki | 2 | — | |
JDCJDUHEACMDQD
|
9.2 | IC50 | 3 | — | |
WHFWYHDLWCPIQQ
|
9.2 | IC50 | 2 | — | |
ZVNVTNQZTVZTHC
|
9.2 | Ki | 2 | — | |
BJKZKIIDDOPGSL
|
9.2 | Ki | 2 | — | |
IBUSAMQQDAHRGB
|
9.2 | Ki | 2 | — | |
VZWISUYRLCJYFG
|
9.1 | Ki | 2 | — | |
DWZCARYLQUBAOL
|
9.1 | Ki | 2 | — | |
SMHPRXGGKKOZAK
|
9.1 | Ki | 2 | — | |
RFCWVWJZLAAPQL
|
9.1 | IC50 | 2 | — | |
SDFLBLKQMVKOIZ
|
9.1 | IC50 | 2 | — | |
SDLXTGGQDFKXAN
|
9.1 | IC50 | 2 | — | |
DDSKNUPYSLTOOQ
|
9.1 | Ki | 2 | — | |
GFTAEBJAMHCGNW
|
9.1 | IC50 | 2 | — | |
XDVFKCZZXOGEMN
|
9.1 | IC50 | 2 | — | |
XDVFKCZZXOGEMN
|
9.1 | IC50 | 2 | — | |
DLHYGFYTVIBNSH
|
9.0 | IC50 | 2 | — | |
JNPWHXLRBKEIPP
|
9.0 | IC50 | 2 | — | |
MSNDBGHTMCHRQB
|
9.0 | IC50 | 3 | — | |
QTWZLGJMQCNKFJ
|
9.0 | IC50 | 2 | — |