Target Details
| UniProt AC | P34896 |
|---|---|
| Gene Symbol | SHMT1 |
| Protein Name | Serine hydroxymethyltransferase, cytosolic |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00464 (SHMT) |
Summary
- Multi-target molecules 29
- Clinical molecules 0
- Avg pChEMBL 7.75
KEGG Pathways (9)
Active Molecules (29)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
RULYJGNVROYLMC
|
9.8 | IC50 | 2 | — | |
SBXSFCJRQHFJCU
|
9.4 | IC50 | 2 | — | |
OVLFRYCELXBGIP
|
9.1 | IC50 | 2 | — | |
ANVDODRMYMOZAX
|
9.1 | IC50 | 2 | — | |
ANVDODRMYMOZAX
|
9.0 | IC50 | 2 | — | |
STIXDXOWMOSMLS
|
8.8 | IC50 | 2 | — | |
MNQKCFVRMKFSRS
|
8.7 | IC50 | 2 | — | |
IFXAOLUJJPGTRO
|
8.6 | IC50 | 2 | — | |
SJUPLONWLFCZIO
|
8.4 | IC50 | 2 | — | |
KFRRRBLZZZIORF
|
8.1 | IC50 | 2 | — | |
ABVQWOKKUNIONW
|
8.1 | IC50 | 2 | — | |
VVVOFJZXKJKHTD
|
8.1 | IC50 | 2 | — | |
XFGGMKRSVAYKAP
|
8.0 | IC50 | 2 | — | |
GMSUWQXMBWFYRQ
|
7.9 | IC50 | 2 | — | |
XFGGMKRSVAYKAP
|
7.8 | IC50 | 2 | — | |
IWUCUJZMKDHLOF
|
7.8 | IC50 | 2 | — | |
NOKJZHRLDAOFCV
|
7.5 | IC50 | 2 | — | |
XZBVRHHXEIXBEI
|
7.5 | IC50 | 2 | — | |
LAKFZGRXOWFMOU
|
7.4 | IC50 | 2 | — | |
CCSMRAGPBNANSC
|
7.2 | Ki | 3 | — | |
XXFHLIRRVPIIOL
|
7.0 | IC50 | 2 | — | |
RQAHNHUMMCUWMX
|
6.9 | Ki | 3 | — | |
SIJLVGGRNZJIBK
|
6.7 | IC50 | 2 | — | |
SPSKTOLBULFCQW
|
6.7 | Ki | 2 | — | |
JYQMTHLVOBDSKN
|
6.4 | IC50 | 2 | — | |
TWOHIZSLHHEBFW
|
6.3 | IC50 | 2 | — | |
SPNNZCKKJSFKKB
|
6.2 | IC50 | 2 | — | |
VOXSIQHYUGLGIP
|
6.1 | Ki | 2 | — | |
IBENGLXKAUDADJ
|
6.0 | Ki | 2 | — |