Target Details
| UniProt AC | P30837 |
|---|---|
| Gene Symbol | ALDH1B1 |
| Protein Name | Aldehyde dehydrogenase X, mitochondrial |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00171 (Aldedh) |
Summary
- Multi-target molecules 8
- Clinical molecules 0
- Avg pChEMBL 7.01
KEGG Pathways (15)
- Alcoholic liver disease
- Arginine and proline metabolism
- Ascorbate and aldarate metabolism
- Biosynthesis of cofactors
- Fatty acid degradation
- Glycerolipid metabolism
- Glycolysis / Gluconeogenesis
- Histidine metabolism
- Lysine degradation
- Metabolic pathways
- Pantothenate and CoA biosynthesis
- Pyruvate metabolism
- Tryptophan metabolism
- Valine, leucine and isoleucine degradation
- beta-Alanine metabolism
Active Molecules (8)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
MWKSRKSEWLRPBL
|
8.1 | Kd | 1075 | — | |
ZCCPLJOKGAACRT
|
8.0 | Kd | 599 | — | |
ZPRBNMALSYXIOM
|
7.1 | IC50 | 3 | — | |
XHLNYQWMGGXIOS
|
7.0 | IC50 | 4 | — | |
RMGKMCRYPIGTNK
|
6.8 | IC50 | 5 | — | |
WXJJMJBXWVJLTL
|
6.5 | IC50 | 4 | — | |
ADGUVFJYVNRVPX
|
6.4 | IC50 | 5 | — | |
WYJIAHORHOZJHY
|
6.1 | IC50 | 4 | — |