BDKRB2 — MultiTargetDB

Target Details

UniProt AC	`P30411`
Gene Symbol	BDKRB2
Protein Name	B2 bradykinin receptor
Organism	Homo sapiens
Entry Name
Organism Category	Human
Pfam Domains	PF00001 (7tm_1)

Summary

Multi-target molecules 32
Clinical molecules 24
Avg pChEMBL 8.3

KEGG Pathways (10)

Top Co-occurrence Targets

BDKRB1 28 shared
TACR1 2 shared
RORB 1 shared
SLC6A3 1 shared
RORC 1 shared
HTR6 1 shared
NPY2R 1 shared
MTNR1A 1 shared
HTR5A 1 shared
HTR3A 1 shared

Active Molecules (32)

InChIKey	pChEMBL	Type	Targets	Clinical
`QXZGBUJJYSLZLT`	11.0	pIC50	2	Yes
`DSKXSKYPLRUWNI`	10.6	pIC50	2	Yes
`DSKXSKYPLRUWNI`	10.6	pIC50	2	Yes
`PWPVANGLZUNDSV`	10.5	pIC50	2	Yes
`SKEDKPUBPAWRPO`	9.8	pIC50	2	Yes
`UXMVCNAZMAVIBE`	9.7	pIC50	2	Yes
`KULRZBJHHZWTME`	9.1	pIC50	2	Yes
`MDVKPFWDLCCUPM`	9.0	pIC50	2	Yes
`WBBTXKGNCKTYFN`	9.0	pIC50	2	Yes
`WBBTXKGNCKTYFN`	9.0	pIC50	2	Yes
`WRPSCMJWFRBZKH`	8.7	pIC50	2	Yes
`CJKSFDBEHUXSSN`	8.6	pIC50	2	Yes
`ROMRTXMEQJYJJZ`	8.4	IC50	3	—
`YMROZBYZFLPAPA`	8.4	Ki	2	—
`BBKUNIDRTSPPPW`	8.2	pIC50	2	Yes
`DSKXSKYPLRUWNI`	8.0	Ki	2	—
`DHXMASVOPVPEJZ`	7.8	pIC50	2	Yes
`KYIGOCCCBXRHNJ`	7.7	IC50	43	—
`FDNSGRXVGYVALV`	7.5	pIC50	2	Yes
`UQNOVFWEEACSGU`	7.5	pIC50	2	Yes
`FDNSGRXVGYVALV`	7.4	pIC50	2	Yes
`MDVKPFWDLCCUPM`	7.2	pIC50	2	Yes
`RBIXVHPHNGXTCI`	7.2	pIC50	2	Yes
`QKBBGEQUAVGUHW`	7.2	Ki	2	—
`UKMJWGFHXMGRNG`	7.2	Ki	2	—
`PWPVANGLZUNDSV`	7.2	Ki	2	—
`WRPSCMJWFRBZKH`	7.0	pIC50	2	Yes
`KULRZBJHHZWTME`	6.8	pIC50	2	Yes
`IQEQRSGEGRUUMU`	6.2	Ki	2	—
`WBBTXKGNCKTYFN`	6.2	pIC50	2	Yes
`CJKSFDBEHUXSSN`	Clinical	TTD_MultiTarget	2	Yes
`DRZRLKNZUGAIDL`	Clinical	TTD_MultiTarget	2	Yes