Target Details
| UniProt AC | P30281 |
|---|---|
| Gene Symbol | CCND3 |
| Protein Name | G1/S-specific cyclin-D3 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF02984 (Cyclin_C) PF00134 (Cyclin_N) |
Summary
- Multi-target molecules 656
- Clinical molecules 33
- Avg pChEMBL 7.59
KEGG Pathways (17)
- Cell cycle
- Cellular senescence
- Chemical carcinogenesis - receptor activation
- Epstein-Barr virus infection
- Focal adhesion
- Hippo signaling pathway
- Human T-cell leukemia virus 1 infection
- Human papillomavirus infection
- Influenza A
- Integrin signaling
- JAK-STAT signaling pathway
- Measles
- PI3K-Akt signaling pathway
- Pathways in cancer
- Viral carcinogenesis
- Wnt signaling pathway
- p53 signaling pathway
Associated Diseases (1)
Active Molecules (656)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
OUSFTKFNBAZUKL
|
6.0 | IC50 | 58 | Yes | |
JPJBKLUESOYNLD
|
6.0 | IC50 | 4 | — | |
FWPHUFSCXZZXFS
|
6.0 | IC50 | 2 | — | |
OPUYYVDBFJRZHZ
|
6.0 | IC50 | 4 | — | |
TUHRSPDOKFFKGG
|
6.0 | Ki | 5 | — | |
WYBDIAZRTPZHAJ
|
6.0 | IC50 | 6 | — |