Target Details
| UniProt AC | P29992 |
|---|---|
| Gene Symbol | GNA11 |
| Protein Name | Guanine nucleotide-binding protein subunit alpha-11 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00503 (G-alpha) |
Summary
- Multi-target molecules 2
- Clinical molecules 0
- Avg pChEMBL 7.16
KEGG Pathways (21)
- Aldosterone synthesis and secretion
- Amoebiasis
- Calcium signaling pathway
- Chagas disease
- Cholinergic synapse
- Cortisol synthesis and secretion
- Cushing syndrome
- Gap junction
- GnRH secretion
- GnRH signaling pathway
- Growth hormone synthesis, secretion and action
- Hormone signaling
- Human cytomegalovirus infection
- Human immunodeficiency virus 1 infection
- Insulin secretion
- Long-term depression
- Neuroactive ligand signaling
- Parathyroid hormone synthesis, secretion and action
- Pathways in cancer
- Vascular smooth muscle contraction
- cGMP-PKG signaling pathway
Associated Diseases (1)
Top Co-occurrence Targets
- GNAQ 2 shared
Active Molecules (2)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
IMXKHFILKMPFGB
|
7.5 | IC50 | 2 | — | |
QVYLWCAYZGFGNF
|
6.8 | IC50 | 2 | — |