Target Details
| UniProt AC | P29965 |
|---|---|
| Gene Symbol | CD40LG |
| Protein Name | CD40 ligand |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00229 (TNF) |
Summary
- Multi-target molecules 4
- Clinical molecules 0
- Avg pChEMBL 6.43
KEGG Pathways (14)
- Allograft rejection
- Asthma
- Autoimmune thyroid disease
- Cell adhesion molecule (CAM) interaction
- Cytokine-cytokine receptor interaction
- Intestinal immune network for IgA production
- Lipid and atherosclerosis
- Malaria
- NF-kappa B signaling pathway
- Primary immunodeficiency
- Systemic lupus erythematosus
- T cell receptor signaling pathway
- Toxoplasmosis
- Viral myocarditis
Associated Diseases (1)
Top Co-occurrence Targets
- CD40 4 shared
Active Molecules (4)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
BZAWLSZPOBGURT
|
6.8 | IC50 | 2 | — | |
XCTCVKFDAODCNM
|
6.5 | IC50 | 2 | — | |
LZHHABGKCSZVBE
|
6.4 | IC50 | 2 | — | |
NWRNKESWUJPLPC
|
6.0 | IC50 | 2 | — |