Target Details
| UniProt AC | P27815 |
|---|---|
| Gene Symbol | PDE4A |
| Protein Name | 3',5'-cyclic-AMP phosphodiesterase 4A |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF18100 (PDE4_UCR) PF00233 (PDEase_I) |
Summary
- Multi-target molecules 1,354
- Clinical molecules 3
- Avg pChEMBL 7.5
KEGG Pathways (5)
Active Molecules (1,354)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
OXMNWHWSPHHKPG
|
10.5 | IC50 | 7 | — | |
UXEIWFVTAFVRHB
|
10.5 | IC50 | 6 | — | |
VCFBPAOSTLMYIV
|
10.4 | IC50 | 4 | — | |
UJBRFXVBFHYAKT
|
10.3 | IC50 | 4 | — | |
GYGRWOSNDXPNMP
|
10.3 | IC50 | 4 | — | |
LBWCSPVCIHIOEB
|
10.3 | IC50 | 4 | — | |
AWTHUFZDVFPXSS
|
10.3 | IC50 | 4 | — | |
REEYYMDAALTGHS
|
10.2 | IC50 | 2 | — | |
XRSKAWJXBDACRF
|
10.2 | IC50 | 2 | — | |
HKDLWHWCJPIJIX
|
10.1 | IC50 | 4 | — | |
VXYDHPDQMSVQCU
|
10.1 | IC50 | 4 | — | |
ZWJIUZQJDZNYBS
|
10.1 | IC50 | 4 | — | |
CEHKCCIAAOPSSX
|
10.0 | IC50 | 4 | — | |
MXZUUMPZFQCEKE
|
10.0 | IC50 | 4 | — | |
QIGAIOOPCCZYDO
|
10.0 | IC50 | 4 | — | |
RKHSMIVCRGVSAI
|
10.0 | IC50 | 4 | — | |
UJLHNYPXKZJKLV
|
10.0 | IC50 | 24 | — | |
XOGGQRYYRPKZIC
|
10.0 | IC50 | 4 | — | |
JTKNXLCKQCJQKS
|
9.9 | IC50 | 4 | — | |
PHDZHEYWNQYONL
|
9.9 | IC50 | 4 | — | |
KXCOKRBRUWINCT
|
9.9 | IC50 | 24 | — | |
GEMOJLFQNTTWCD
|
9.8 | IC50 | 4 | — | |
MAKUTQULODJGHN
|
9.8 | IC50 | 4 | — | |
TWGTWIKMLGTGCM
|
9.8 | IC50 | 4 | — | |
BQEBFXOTHOXEOX
|
9.8 | IC50 | 4 | — | |
KPFFPWNKWSYQFT
|
9.8 | IC50 | 24 | — | |
LIFZRCXARBAEEF
|
9.8 | IC50 | 4 | — | |
MZWIXTAQIAHGBV
|
9.8 | IC50 | 7 | — | |
CPPUHWHUGUNWMP
|
9.8 | IC50 | 2 | — | |
HJPRDDKCXVCFOH
|
9.8 | IC50 | 4 | — | |
MUXCFHMDQSBSSH
|
9.8 | IC50 | 4 | — | |
OPTQGHCAPKNFRD
|
9.8 | IC50 | 4 | — | |
IMPXLKKWNSKICE
|
9.7 | IC50 | 4 | — | |
JTSJSXZAIAWVFR
|
9.7 | IC50 | 4 | — | |
FYJSBMKSVVAUMJ
|
9.7 | IC50 | 4 | — | |
ALYHHAAECIOHDF
|
9.7 | IC50 | 4 | — | |
DMMULEHMESXRSD
|
9.7 | IC50 | 6 | — | |
FLCHWTIQFVHCMK
|
9.7 | IC50 | 4 | — | |
FQXMGNGXEISOLZ
|
9.7 | IC50 | 4 | — | |
IJGHHSIAVWWRGI
|
9.7 | IC50 | 4 | — | |
UZMVNVNNMNSBTP
|
9.7 | IC50 | 4 | — | |
JTNDJOKFPXYVIU
|
9.7 | IC50 | 4 | — | |
XQQZUVVOBMJVNU
|
9.7 | IC50 | 4 | — | |
GZIRZQKLGPQGCB
|
9.6 | IC50 | 4 | — | |
LAQFTZISVWQAKB
|
9.6 | IC50 | 4 | — | |
HFVIXIRCNYJPAT
|
9.6 | IC50 | 4 | — | |
NLLFTEQPVLBKFG
|
9.6 | IC50 | 4 | — | |
BSVWZNRPPXVNQI
|
9.6 | IC50 | 4 | — | |
PZCMRYAWWGWNEQ
|
9.6 | IC50 | 4 | — | |
CGGDBFMTDWNCOY
|
9.6 | IC50 | 2 | — |