Target Details
| UniProt AC | P26010 |
|---|---|
| Gene Symbol | ITGB7 |
| Protein Name | Integrin beta-7 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF07974 (EGF_2) PF08725 (Integrin_b_cyt) PF00362 (Integrin_beta) PF17205 (PSI_integrin) |
Summary
- Multi-target molecules 355
- Clinical molecules 0
- Avg pChEMBL 7.31
KEGG Pathways (13)
- Arrhythmogenic right ventricular cardiomyopathy
- Cell adhesion molecule (CAM) interaction
- Cytoskeleton in muscle cells
- Dilated cardiomyopathy
- ECM-receptor interaction
- Focal adhesion
- Human papillomavirus infection
- Hypertrophic cardiomyopathy
- Integrin signaling
- Intestinal immune network for IgA production
- PI3K-Akt signaling pathway
- Regulation of actin cytoskeleton
- Transcriptional misregulation in cancer
Active Molecules (355)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
SPYRCTMYBNFJRX
|
6.1 | IC50 | 3 | — | |
IKCCBHPHWWMTHQ
|
6.1 | IC50 | 2 | — | |
QBLBCXCNIKAKNO
|
6.1 | IC50 | 3 | — | |
CELGRUOLPJJNJO
|
6.0 | IC50 | 3 | — | |
UDLGQJHWEZPISX
|
6.0 | IC50 | 2 | — |