Target Details
| UniProt AC | P25963 |
|---|---|
| Gene Symbol | NFKBIA |
| Protein Name | NF-kappa-B inhibitor alpha |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF12796 (Ank_2) |
Summary
- Multi-target molecules 1
- Clinical molecules 0
- Avg pChEMBL 6.13
KEGG Pathways (50)
- Adipocytokine signaling pathway
- Alcoholic liver disease
- Apoptosis
- B cell receptor signaling pathway
- C-type lectin receptor signaling pathway
- Cadherin signaling
- Chagas disease
- Chemical carcinogenesis - reactive oxygen species
- Chemokine signaling pathway
- Chronic myeloid leukemia
- Coronavirus disease - COVID-19
- Cytosolic DNA-sensing pathway
- Epithelial cell signaling in Helicobacter pylori infection
- Epstein-Barr virus infection
- Hepatitis B
- Hepatitis C
- Herpes simplex virus 1 infection
- Human T-cell leukemia virus 1 infection
- Human cytomegalovirus infection
- Human immunodeficiency virus 1 infection
- IL-17 signaling pathway
- Influenza A
- Insulin resistance
- Kaposi sarcoma-associated herpesvirus infection
- Legionellosis
- Leishmaniasis
- Lipid and atherosclerosis
- Measles
- NF-kappa B signaling pathway
- NOD-like receptor signaling pathway
- Neurotrophin signaling pathway
- Osteoclast differentiation
- PD-L1 expression and PD-1 checkpoint pathway in cancer
- Pathogenic Escherichia coli infection
- Pathways in cancer
- Prostate cancer
- RIG-I-like receptor signaling pathway
- Relaxin signaling pathway
- Salmonella infection
- Shigellosis
- Small cell lung cancer
- T cell receptor signaling pathway
- TNF signaling pathway
- Th1 and Th2 cell differentiation
- Th17 cell differentiation
- Toll-like receptor signaling pathway
- Toxoplasmosis
- Viral carcinogenesis
- Yersinia infection
- cAMP signaling pathway
Associated Diseases (2)
Top Co-occurrence Targets
- EPHA2 1 shared
Active Molecules (1)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
ANZRNHPEVLXURS
|
6.1 | Kd | 2 | — |