Target Details
UniProt ACP25779
Gene SymbolN/A
Protein NameCruzipain
OrganismTrypanosoma cruzi
Entry Name
Organism Category Pathogen
Pfam Domains PF12131 (DUF3586) PF08246 (Inhibitor_I29) PF00112 (Peptidase_C1)
UniProt
Summary
  • Multi-target molecules 173
  • Clinical molecules 0
  • Avg pChEMBL 7.67
Top Co-occurrence Targets
Active Molecules (173)
InChIKey pChEMBL Type Targets Clinical
WHNDEIMPFCLXJS 7.3 Ki 4 —
SHSWGVYDDDLDDL 7.3 Ki 2 —
CIHXWBMSCJPIFY 7.3 Ki 2 —
GFHZEVBJLGUWPM 7.3 IC50 2 —
HSDLXMXANDTTHN 7.3 Ki 2 —
ILDMHYFHSBBUCU 7.3 IC50 2 —
ILDMHYFHSBBUCU 7.3 IC50 2 —
WWJXDXQVSFLZSC 7.3 Ki 2 —
XBQOGPRXCCTYMI 7.3 IC50 2 —
FWDHQPCCEQRRCZ 7.2 Ki 2 —
JQWZVHIYHXTNRV 7.2 Ki 2 —
MCFIRXUXLURQKO 7.2 Ki 2 —
RUJRINHGQAHHCG 7.2 Ki 2 —
VVENSUKHMNEUHS 7.2 Ki 2 —
HFWZVGXIRYNTPC 7.1 Ki 2 —
GFKPWKCDJBRXQK 7.1 IC50 2 —
IZCFERYAEIDCSD 7.1 Ki 2 —
MEBPGJFXXVRICE 7.1 IC50 4 —
NOWCNBDPTWLOJL 7.1 IC50 2 —
NOWCNBDPTWLOJL 7.1 IC50 2 —
YUJAVMJKRUKNMF 7.1 IC50 2 —
KHXWGZGVODXABJ 7.0 Ki 4 —
WBIKZQWGHHXZTG 7.0 IC50 2 —
WBIKZQWGHHXZTG 7.0 IC50 2 —
WJQYKRIBWNZUHM 7.0 IC50 2 —
WJQYKRIBWNZUHM 7.0 IC50 2 —
FWIVDMJALNEADT 6.9 Ki 5 —
VZWOGJRVIYJLGW 6.9 Ki 3 —
NGVFUFFEHBAUON 6.9 Ki 4 —
NNULPUWGQGOFSK 6.9 IC50 3 —
RHIHZTLBXHBNPQ 6.9 Ki 4 —
RJRIHEGJRAJLIX 6.8 Ki 2 —
YDBHYROCBRFPCV 6.8 Ki 2 —
UDPRWQLZVHVIPZ 6.8 Ki 3 —
UYDFFWBONYOJKU 6.7 IC50 3 —
DXLLSNZJTDGBRA 6.7 IC50 4 —
KYIOYAKHUFJXLN 6.7 Ki 2 —
QDXJMPRQUCWKKV 6.7 Ki 2 —
XOBXSIZLGQEDSF 6.7 IC50 2 —
XOBXSIZLGQEDSF 6.7 IC50 2 —
GMUXXTCOBZDVFS 6.7 Ki 4 —
TVUDUONIRJXXCP 6.7 Ki 4 —
NFHCBRWUVWGFHZ 6.6 Ki 4 —
PIEOUSVKYUIHRE 6.6 Ki 4 —
PXXQXBNYVWENDC 6.6 Ki 2 —
FJXWVAUWWYLARM 6.5 Ki 3 —
FJXWVAUWWYLARM 6.5 Ki 3 —
DSMGEPBRPIEQKD 6.5 IC50 4 —
DSMGEPBRPIEQKD 6.5 IC50 3 —
JRFCJBAMIBGKTB 6.5 IC50 4 —
2D structure