Target Details
| UniProt AC | P23921 |
|---|---|
| Gene Symbol | RRM1 |
| Protein Name | Ribonucleoside-diphosphate reductase large subunit |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF03477 (ATP-cone) PF02867 (Ribonuc_red_lgC) PF00317 (Ribonuc_red_lgN) |
Summary
- Multi-target molecules 296
- Clinical molecules 0
- Avg pChEMBL 6.77
KEGG Pathways (6)
Associated Diseases (1)
Active Molecules (296)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
GUYBCDOHXGRHHH
|
7.1 | IC50 | 4 | — | |
NANLDQWTKYLHLN
|
7.1 | IC50 | 4 | — | |
OLUJVKIVDAIVMP
|
7.1 | IC50 | 4 | — | |
WIXMVAVOJYRHDC
|
7.1 | IC50 | 4 | — | |
WXLHBKPIRLKYAH
|
7.1 | IC50 | 5 | — | |
YKEQFYIPBQQNKQ
|
7.1 | IC50 | 2 | — | |
YLGULXRNPXJXHL
|
7.1 | IC50 | 4 | — | |
MJUQLGDPJKYTLP
|
7.1 | IC50 | 2 | — | |
VSCQSEPSIXHGTJ
|
7.1 | IC50 | 2 | — | |
WGFZESGMAYFITP
|
7.1 | IC50 | 4 | — | |
AFDDBGDYUYJYLZ
|
7.0 | IC50 | 4 | — | |
AFUCVSLMRJHCDM
|
7.0 | IC50 | 4 | — | |
HDACFKYOBJLCPQ
|
7.0 | IC50 | 2 | — | |
JSCWCLIBZAMGMF
|
7.0 | IC50 | 4 | — | |
PXUHBJFMMXIUJP
|
7.0 | IC50 | 4 | — | |
RIVYHLQVCQYKAV
|
7.0 | IC50 | 4 | — | |
UOLFNMRHECBLBA
|
7.0 | IC50 | 4 | — | |
VIEBUZHAFUWGGS
|
7.0 | IC50 | 4 | — | |
XUJYIQJVTCUDPS
|
7.0 | IC50 | 4 | — | |
BCPVTLUZROTVTR
|
7.0 | IC50 | 4 | — | |
CYTRNWHHJCCGBY
|
7.0 | IC50 | 4 | — | |
FBYQQBWWVQINBI
|
7.0 | IC50 | 4 | — | |
GEALCDALCGCQFR
|
7.0 | IC50 | 4 | — | |
GHVVHNWTSPTZKS
|
7.0 | IC50 | 4 | — | |
GNHYCLNLNXMESJ
|
7.0 | IC50 | 4 | — | |
ICAJLQZVLFKOOK
|
7.0 | IC50 | 4 | — | |
IJAJBUCUDNCTMV
|
7.0 | IC50 | 3 | — | |
NSQWGNSKLPITOS
|
7.0 | IC50 | 2 | — | |
QUYWXQCGHJOUSX
|
7.0 | IC50 | 4 | — | |
RJKOEXRPQFHGFU
|
7.0 | IC50 | 4 | — | |
RUCYNEILMKNPMV
|
7.0 | IC50 | 4 | — | |
VAVAMZWIHKTIFJ
|
7.0 | IC50 | 4 | — | |
WGFZESGMAYFITP
|
7.0 | IC50 | 4 | — | |
XZPLJXKNDMOTKN
|
7.0 | IC50 | 4 | — | |
AMKGONWYZZPTIL
|
7.0 | IC50 | 4 | — | |
BDHJGNMIOKDXBI
|
7.0 | IC50 | 4 | — | |
CITXQYRJEHWFPC
|
7.0 | IC50 | 4 | — | |
FUBPLGZZKBHUDG
|
7.0 | IC50 | 4 | — | |
FVXKERPIGVCGIR
|
7.0 | IC50 | 4 | — | |
QSAKHCKHBZBOKB
|
7.0 | IC50 | 4 | — | |
ROJTXNMSUIEMFK
|
7.0 | IC50 | 4 | — | |
UAIKSDXRQZELHM
|
7.0 | IC50 | 4 | — | |
AMKGONWYZZPTIL
|
6.9 | IC50 | 4 | — | |
CBWJILLOTDNCCG
|
6.9 | IC50 | 2 | — | |
DYUCIPGRLQNPOD
|
6.9 | IC50 | 4 | — | |
IJMVYQUDORUVOI
|
6.9 | IC50 | 4 | — | |
ODRXKRITNIHJDG
|
6.9 | IC50 | 4 | — | |
RIJICWHWOASZHK
|
6.9 | IC50 | 2 | — | |
UDXBARFJUKBPBJ
|
6.9 | IC50 | 5 | — | |
DSYOVHINHROBKN
|
6.9 | IC50 | 4 | — |