Target Details
| UniProt AC | P23368 |
|---|---|
| Gene Symbol | ME2 |
| Protein Name | NAD-dependent malic enzyme, mitochondrial |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00390 (malic) PF03949 (Malic_M) |
Summary
- Multi-target molecules 16
- Clinical molecules 0
- Avg pChEMBL 6.62
KEGG Pathways (2)
Active Molecules (16)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
MWKSRKSEWLRPBL
|
7.5 | Kd | 1075 | — | |
ZVWPAJGWVHTYOY
|
6.8 | IC50 | 3 | — | |
VEAAIEOUCDGSDL
|
6.7 | IC50 | 3 | — | |
JJFJQFJFFVLMCX
|
6.7 | IC50 | 3 | — | |
MEFDXVJUTKLMFA
|
6.7 | IC50 | 2 | — | |
YIAYJWOHRNVYRN
|
6.7 | IC50 | 3 | — | |
BGTWBUGCUCWIOQ
|
6.7 | IC50 | 3 | — | |
PNZZNNLKSKJYFE
|
6.7 | IC50 | 3 | — | |
RDNCXCMHGHXQNH
|
6.6 | IC50 | 3 | — | |
AHBHZZLUODBWMS
|
6.6 | IC50 | 3 | — | |
UMSFQBOKDFFFTQ
|
6.6 | IC50 | 3 | — | |
ANKCAVFAEXIRFY
|
6.5 | IC50 | 3 | — | |
IXKBNMZSPYLPLY
|
6.4 | IC50 | 3 | — | |
SOKWAQDMVUMRKD
|
6.4 | IC50 | 3 | — | |
NESIORPNFVEQNP
|
6.4 | IC50 | 3 | — | |
UXRDRISGQSMTIM
|
6.0 | IC50 | 2 | — |