Target Details
UniProt ACP22894
Gene SymbolMMP8
Protein NameNeutrophil collagenase
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF00045 (Hemopexin) PF00413 (Peptidase_M10) PF01471 (PG_binding_1)
UniProt
Summary
  • Multi-target molecules 934
  • Clinical molecules 624
  • Avg pChEMBL 7.65
Top Co-occurrence Targets
Active Molecules (934)
InChIKey pChEMBL Type Targets Clinical
SUSMVCKSLVPRCL 8.2 IC50 5 —
CNDCCBOSTVCBMM 8.2 IC50 7 Yes
CVRRBTAXFZBMPH 8.2 Ki 4 Yes
PCOMQZCYLOTKTN 8.2 IC50 5 Yes
SBYCYYMPCYJMTP 8.2 IC50 7 Yes
SBOCVCYAEHVMEA 8.2 Ki 4 Yes
AMHJUVNJSCPYSD 8.2 Ki 3 —
ATNNMKHWMHMLHP 8.2 Ki 7 Yes
GFUITADOEPNRML 8.2 IC50 8 Yes
JYPUUSQERHUIDJ 8.2 Ki 6 Yes
LWTYDGJEOHWGQD 8.2 Ki 4 Yes
MMCVYPKEJGVLMH 8.2 Ki 7 Yes
NKGRTRASISLCCZ 8.2 IC50 10 Yes
NKTGQIQCKMXEOS 8.2 IC50 3 Yes
URNQLXVLIBILTE 8.2 Ki 4 Yes
ITADELAVAWJACR 8.1 IC50 2 Yes
WUXSSALNWBMRKU 8.1 Ki 4 Yes
GBFCSIJILLHVFK 8.1 Ki 4 Yes
PJVJLPSYNZOOCE 8.1 Ki 4 Yes
XQEHCUFTCDJVSN 8.1 Ki 4 Yes
ANZWBBMLNAIBAB 8.1 IC50 4 —
BXZZUNDHINECCH 8.1 IC50 3 Yes
CCOMNSWISYQLEX 8.1 IC50 3 Yes
COMOZYQMQPSLMB 8.1 Ki 4 Yes
DCSHLVVGHNRVCO 8.1 Ki 7 Yes
HVHBPSLGXXXKOR 8.1 Ki 7 Yes
MYZZCJKXPLJTGX 8.1 IC50 3 Yes
VDUBALDTEGAJSW 8.1 Ki 7 Yes
XOVSRAFNJNQNRK 8.1 IC50 4 Yes
VWIDRIAWTQJPLN 8.1 Ki 4 Yes
CUKATAAPVFYVIL 8.1 IC50 9 —
DOXXSEYJDIFFAY 8.1 Ki 5 Yes
DVXDZENYHAGFRW 8.1 Ki 4 Yes
HIWQTXDWQYKMGH 8.1 Ki 7 Yes
JIRXORZYIXSWOB 8.1 Ki 11 Yes
PCRITYAGTCCZEK 8.1 Ki 7 Yes
PZNZBFBEAZCEQK 8.1 IC50 3 Yes
SESYXDSEOCRODR 8.1 Ki 7 Yes
VKUYLANQOAKALN 8.1 Ki 7 Yes
ZBTKKYFIZQHNDQ 8.1 IC50 7 Yes
RBZQWZODGBMNHX 8.0 Ki 6 Yes
VUKNURXXGDIFMO 8.0 Ki 4 Yes
FOSWRYKPHVPIDJ 8.0 IC50 8 Yes
QVHYJMPAZNGFHN 8.0 Ki 6 —
UXURFMZZZWZYFW 8.0 IC50 6 Yes
DFPDFXUEOXPMIV 8.0 Ki 7 Yes
DTFUJQWTCDBNIX 8.0 IC50 3 Yes
DZOZBHZWCFMSKH 8.0 IC50 4 Yes
FPSMXPGSVWPWCG 8.0 IC50 8 —
GXZSIAVJNPWNMR 8.0 IC50 7 Yes
2D structure