Target Details
UniProt ACP22894
Gene SymbolMMP8
Protein NameNeutrophil collagenase
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF00045 (Hemopexin) PF00413 (Peptidase_M10) PF01471 (PG_binding_1)
UniProt
Summary
  • Multi-target molecules 934
  • Clinical molecules 624
  • Avg pChEMBL 7.65
Top Co-occurrence Targets
Active Molecules (934)
InChIKey pChEMBL Type Targets Clinical
UEXHODHUQXSZDN 8.4 Ki 6 Yes
UNRFEBNSHUZKHJ 8.4 IC50 3 Yes
WYBFHVSAXDKMJV 8.4 Ki 4 Yes
XJMDDZUUIUEEJH 8.4 Ki 5 —
YRUNEWMUGNJMAR 8.4 Ki 7 Yes
VLTOUUSTKONGKC 8.4 Ki 10 Yes
DVBWYFQJLIUTJA 8.4 Ki 4 Yes
LKJAZJMUPQPJNA 8.4 IC50 6 Yes
BSIZUMJRKYHEBR 8.4 IC50 15 Yes
BAIUIZQDBMFOMK 8.3 Ki 4 Yes
BVONHINTCXADCU 8.3 Ki 4 Yes
IWLYSDNBOSWMRQ 8.3 Ki 4 Yes
QQDWEVONJRXVDB 8.3 Ki 6 Yes
NCIVMBVZAUECOS 8.3 Ki 5 Yes
IWTGCCHOUSDKHV 8.3 Ki 10 Yes
QRXOZHSEEGNRFC 8.3 IC50 8 Yes
DMOIDCGAIGWXGJ 8.3 Ki 7 Yes
GKLOCXVNLLEZMX 8.3 IC50 4 —
IEHSRERHOYOHOA 8.3 Ki 6 Yes
IVPPTWCRAFCOFJ 8.3 IC50 5 —
JXMJSOSLBMBYGM 8.3 IC50 4 —
KLWUGXOQJJWEBZ 8.3 Ki 5 —
MKTUSESWUSYVIL 8.3 IC50 3 Yes
NFDNOGJHVSTSMJ 8.3 Ki 7 Yes
NXCSXUBVRRHHLE 8.3 IC50 4 —
PCQHVURJJBFBQG 8.3 Ki 7 Yes
RIOJMNDNYHZZFM 8.3 Ki 7 Yes
UOHZYJYLFKMPMQ 8.3 Ki 7 Yes
ZOJMJLMSZDGBHC 8.3 IC50 2 —
UTERPWJSMDDIGY 8.3 Ki 8 Yes
YOMXWXIANUYIMH 8.3 IC50 10 Yes
GBQQHIUTXSUOPE 8.3 Ki 10 Yes
KGUVBHLPMGERAT 8.3 IC50 8 Yes
QZRDSGNFNCBFPU 8.3 Ki 4 Yes
UYFGGWJRPCRSHW 8.3 IC50 7 Yes
XNDAUZRSIAEAAR 8.3 Ki 6 —
UFJUEKAJZPTZED 8.3 Ki 4 Yes
ZHENEPVPETWBJM 8.3 Ki 8 Yes
NJSAPXUDAYVTFL 8.2 Ki 7 Yes
QUIDRRLYQSJQMX 8.2 Ki 4 Yes
WEACEEZKOJLZFG 8.2 Ki 7 Yes
XHLWYEWXYHRDQW 8.2 Ki 4 Yes
YJKZJSXUMXIJNB 8.2 Ki 3 —
JHSGRRNCQDDQBC 8.2 IC50 9 —
UKNOMEZXDWRZAF 8.2 Ki 4 Yes
IYJLBIPCLHKYKU 8.2 Ki 5 Yes
SRBWJOFRJIEWKS 8.2 IC50 7 Yes
DUCBSHDQTBWWLC 8.2 Ki 7 Yes
OFIZOTOQCJTVRO 8.2 Ki 4 Yes
SUSMVCKSLVPRCL 8.2 IC50 7 Yes
2D structure