Target Details
UniProt ACP22894
Gene SymbolMMP8
Protein NameNeutrophil collagenase
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF00045 (Hemopexin) PF00413 (Peptidase_M10) PF01471 (PG_binding_1)
UniProt
Summary
  • Multi-target molecules 934
  • Clinical molecules 624
  • Avg pChEMBL 7.65
Top Co-occurrence Targets
Active Molecules (934)
InChIKey pChEMBL Type Targets Clinical
YNCNUFDRUOIACX 7.7 IC50 3 Yes
ZQJORJBIVFLYIE 7.7 IC50 3 Yes
GPKYERMOQBHGRC 7.7 Ki 4 Yes
LOYIGNDQOZNJNZ 7.7 Ki 7 Yes
LXWCLFCLBYYKME 7.7 IC50 4 —
MXZLDTSVPDTTAN 7.7 Ki 7 Yes
PFPVZWIKTNGHGO 7.7 Ki 7 Yes
RQCBSNJRFVZHOS 7.7 IC50 10 Yes
WPZMNBVWWODJJH 7.7 IC50 4 —
YNSXKATXVIZKSB 7.7 IC50 5 —
MFNVPUYZKNRAKT 7.7 IC50 4 —
ONOMIQQPBDQZDA 7.7 Ki 7 Yes
SQKUIDNBYAHJQB 7.7 IC50 5 —
JGJZJJQMNAKKDG 7.6 Ki 7 Yes
ZGSTVUAZFACDLH 7.6 Ki 7 —
CTEBTZSRXSZTCW 7.6 Ki 7 Yes
FAJZOFHZLDUFEM 7.6 Ki 6 Yes
FGDQQAHGMHOQDV 7.6 Ki 5 Yes
FTUOECQUSPMQQZ 7.6 Ki 7 Yes
HOSIVTBRRYYOOH 7.6 Ki 7 Yes
NJSIDFBPVWKNNH 7.6 Ki 7 Yes
DCCBWHQCASKYJR 7.6 IC50 4 Yes
UERCGTJUVRFNRO 7.6 Ki 6 Yes
PYGZWPVJQNBFNS 7.6 IC50 6 Yes
QZHAFOIXACHKEM 7.6 IC50 5 —
YTZCQIFAVXLXHV 7.6 Ki 7 Yes
LEWMAZXEBPMBSY 7.6 Ki 8 Yes
NGIYDDHHYYPZFT 7.6 Ki 4 Yes
QTXKDSNGGLBSKK 7.6 Ki 7 Yes
RTBPRRSADWSXAD 7.6 Ki 7 Yes
SVUOUTRIPGSFHF 7.6 IC50 5 Yes
SILYLRSFWCVUFM 7.5 Ki 7 Yes
QFPRVWUEWDLNPU 7.5 Ki 7 Yes
RTYBJAJUHLHGKX 7.5 IC50 3 —
SBTMZMWGVVORIF 7.5 IC50 6 Yes
ALDQBTGTDJBFBQ 7.5 Ki 4 Yes
BLDIAFCHXVRHEP 7.5 IC50 3 Yes
CVMQTPIUJOGYIP 7.5 IC50 3 Yes
FJVADCMHIAHBER 7.5 IC50 3 Yes
LERSXUYNVGTZOT 7.5 IC50 3 Yes
OTEWYJZEFZRZKI 7.5 IC50 8 Yes
QPSBVVFMTSFAJY 7.5 IC50 5 Yes
RSWUWSKXIDLCIR 7.5 IC50 4 Yes
UOAOZROEXYBQHF 7.5 IC50 3 Yes
UTVAYVOWTJFEEU 7.5 Ki 7 Yes
VFDSDRZNXLFCFF 7.5 IC50 7 Yes
XIMLFZSNGXTRSL 7.5 IC50 3 Yes
IYEVXJPUTMBOTO 7.5 Ki 7 Yes
QCLOBJCDRHHNCL 7.5 Ki 10 Yes
STMMWXRQAOVQNP 7.5 IC50 5 Yes
2D structure