Target Details
UniProt ACP22894
Gene SymbolMMP8
Protein NameNeutrophil collagenase
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF00045 (Hemopexin) PF00413 (Peptidase_M10) PF01471 (PG_binding_1)
UniProt
Summary
  • Multi-target molecules 934
  • Clinical molecules 624
  • Avg pChEMBL 7.65
Top Co-occurrence Targets
Active Molecules (934)
InChIKey pChEMBL Type Targets Clinical
LOPZANGJCBIBLO 10.7 IC50 4 —
FGQWFLDBWZDRJJ 10.5 IC50 4 —
NRRIJAHIBBGLNH 10.4 IC50 4 —
XJNFMEAYBQFDAS 10.3 IC50 4 —
ROSNVSQTEGHUKU 10.0 IC50 12 Yes
GWQRQVFEMGHPMD 10.0 Ki 10 Yes
SMZZZWJJIWYSNC 10.0 Ki 4 Yes
BOHIPQBVCFMFFK 10.0 Ki 4 Yes
YDSGUUACYYBPLW 10.0 IC50 4 —
NITYDPDXAAFEIT 9.7 Ki 20 Yes
ADDYZQRMSCIHFH 9.7 IC50 4 —
DJQJEICJRBFEOV 9.7 IC50 4 Yes
GDXZUNJRYLVZAT 9.7 IC50 4 —
SMKRBNFEFJZHAI 9.7 IC50 4 —
YSZLQAVPFNEECF 9.6 Ki 4 Yes
GSWRTFGMHRKLKT 9.5 IC50 14 Yes
HJPHCDCNWWBUEA 9.5 Ki 4 Yes
DJASZHFLBWUJAJ 9.5 Ki 7 Yes
NDJSPXLINRRDIS 9.5 Ki 4 Yes
NTDGKPHATDVYNT 9.5 IC50 4 —
UMZQUWRHZNAVMN 9.5 Ki 4 Yes
WUGYYDAXBPEKAI 9.5 IC50 4 —
LUZFASJCLDTWLF 9.5 Ki 4 Yes
VKWHTWCAMYPFQG 9.5 Ki 4 Yes
JBXOGQUSYPCSQK 9.5 Ki 4 Yes
RVKPGECPCLBLDB 9.4 IC50 10 Yes
CJTUBZULFXKTAT 9.4 IC50 10 Yes
YIEJUKBUYFONED 9.4 Ki 4 Yes
GCBPAPVOMPJQHK 9.4 Ki 9 Yes
HYIVZTPHVNIXFU 9.4 IC50 4 Yes
KBZNOZAJAJRTII 9.4 IC50 10 Yes
MFOJAATVHNHXKB 9.4 IC50 4 —
PGEMRSCSFPLCBF 9.4 IC50 8 Yes
REZSPXZZCJTZIK 9.4 IC50 8 Yes
REZSPXZZCJTZIK 9.4 IC50 6 —
WDPVPUZANMBBLA 9.4 Ki 6 —
WNLZTTHHHYZJMB 9.4 IC50 9 Yes
WTEZGXPTIFMTCH 9.4 IC50 4 —
XQXSQQVRMVVPJW 9.4 IC50 8 Yes
JHRIMEDFWCLALJ 9.4 Ki 4 Yes
FNRRTPCWYWKARV 9.4 Ki 4 Yes
CBYPWAIEESKRSM 9.3 Ki 4 Yes
CHAFUQVXOKHDCA 9.3 Ki 5 Yes
GNHMOHGVWISYSN 9.3 Ki 4 Yes
HYGHKRXESWZJHZ 9.3 Ki 4 Yes
DYSNZNGQZPYHHP 9.3 Ki 7 Yes
HFAGTNGCAZYYLZ 9.3 Ki 13 Yes
KYOFVPKPPTUVKK 9.3 IC50 8 Yes
OONXADPQRATYFL 9.3 Ki 5 Yes
TUYLXABAVZEOSZ 9.3 IC50 4 —
2D structure