ACHE — MultiTargetDB

Target Details

UniProt AC	`P22303`
Gene Symbol	ACHE
Protein Name	Acetylcholinesterase
Organism	Homo sapiens
Entry Name
Organism Category	Human
Pfam Domains	PF08674 (AChE_tetra) PF00135 (COesterase)

Summary

Multi-target molecules 1,200
Clinical molecules 23
Avg pChEMBL 7.49

KEGG Pathways (3)

Top Co-occurrence Targets

BCHE 917 shared
BACE1 75 shared
CA2 52 shared
CA1 51 shared
MAOB 47 shared
GSK3B 44 shared
HTR4 29 shared
MAOA 26 shared
GABRB1 21 shared
CHEK1 21 shared

Active Molecules (1,200)

InChIKey	pChEMBL	Type	Targets	Clinical
`ACHUFQQVWLUZBB`	7.4	Ki	3	—
`AKAKQLGKPNQEPO`	7.4	IC50	2	—
`BYVUEKAZFHMRAV`	7.4	Ki	3	—
`CUPIRLCXNXPTKX`	7.4	Ki	3	—
`IEENFQFREXVVSG`	7.4	Ki	3	—
`JVQVWTHTCHSHMY`	7.4	Ki	3	—
`KVRDCAGUOYDFAW`	7.4	IC50	2	—
`RNTAEWUQJLKDIO`	7.4	IC50	2	—
`TWSWYOBXOAKHEL`	7.4	Ki	3	—
`TYGMTYRXRCSMAH`	7.4	IC50	2	—
`UWTPHLBHBPMCCU`	7.4	IC50	2	—
`WLVKCFGDFIGZLL`	7.4	Ki	3	—
`YEWYWWRBZDDFMO`	7.4	Ki	4	—
`GOXLVSZAUDIXPN`	7.4	IC50	4	Yes
`YMBIMUZYHSNFFG`	7.4	IC50	2	—
`YZCXJPDBJRDQRF`	7.4	Ki	2	—
`CIAUOFBPIZNSLU`	7.4	IC50	2	—
`DZXRSFAKIAKMMD`	7.4	IC50	2	—
`JDYATWHUSHCNRV`	7.4	IC50	3	—
`JUWPVFGGRPLWHB`	7.4	IC50	2	—
`PIJVFDBKTWXHHD`	7.4	IC50	3	—
`UTOPPHLSAAJWHX`	7.4	IC50	2	—
`UTQFNPJLIOYJFL`	7.4	IC50	2	—
`YZDRSBRUONQQBH`	7.4	Ki	2	—
`AGMUUBYEBVEYGU`	7.4	IC50	2	—
`LHUNFEXUROHDNV`	7.4	IC50	2	—
`LXUNVISZTGHADK`	7.4	Ki	2	—
`WFLNSPBNQAGFFF`	7.4	IC50	3	—
`ALSNDZNRDOKMKL`	7.4	IC50	2	—
`ALWKGYPQUAPLQC`	7.4	IC50	2	—
`KJVDTZKPWSENAO`	7.4	Ki	2	—
`SIZPSOGNDAPIKG`	7.4	IC50	2	—
`YMUNYIHDWCEAKU`	7.4	IC50	2	—
`LDVMPEHILZZOPY`	7.4	IC50	2	—
`BGDYVTQSRKFIJW`	7.4	Ki	2	—
`DVCKLXBGJWQNDS`	7.4	IC50	3	—
`HFXNFOSTKCPMIS`	7.4	IC50	2	—
`OCOGBPYFWRDLHI`	7.4	IC50	2	—
`CLNWLUWTLQVFCS`	7.3	IC50	3	—
`GMQZFOMNKDBEQB`	7.3	IC50	2	—
`LPMOTUSFDTTWJL`	7.3	IC50	2	—
`PCYHMPUHDXUXAI`	7.3	Ki	2	—
`XSJPRQMWFLDGBX`	7.3	IC50	2	—
`FZBSIZBRWNKKOD`	7.3	IC50	2	—
`GZFFGZKUMVGLEU`	7.3	Ki	2	—
`KECMUWNFMHXRRG`	7.3	IC50	2	—
`NTWXQLUPCDPUOH`	7.3	IC50	2	—
`STHYVJPMYDZLQB`	7.3	IC50	3	—
`WELYXMQWLDVBEU`	7.3	IC50	2	—
`BFCQNBAYDZOIHV`	7.3	IC50	2	—