Target Details
| UniProt AC | P22007 |
|---|---|
| Gene Symbol | RAM1 |
| Protein Name | Protein farnesyltransferase subunit beta |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) |
| Entry Name | |
| Organism Category | Pathogen |
| Pfam Domains | PF00432 (Prenyltrans) |
Summary
- Multi-target molecules 36
- Clinical molecules 3
- Avg pChEMBL 6.91
Active Molecules (36)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
PIOCNQRIEVKMPV
|
10.0 | IC50 | 2 | — | |
OKLOPBKXGZVBCB
|
9.4 | IC50 | 4 | Yes | |
ZIXDDEATQSBHHL
|
9.1 | IC50 | 5 | Yes | |
WPANQPAWMQHJEJ
|
8.3 | IC50 | 4 | Yes | |
MOKAEYICRSCJNS
|
8.2 | IC50 | 2 | — | |
HTBDAWPIJDBOHN
|
7.9 | IC50 | 2 | — | |
ZTORJVQLJHBZSP
|
7.5 | IC50 | 2 | — | |
PTLJRRAZNROODO
|
7.4 | IC50 | 2 | — | |
NSDUAWRPFPUQFV
|
7.1 | Kd | 2 | — | |
PZLVEHFNRCXRNR
|
7.1 | IC50 | 2 | — | |
VWFJDQUYCIWHTN
|
7.1 | Kd | 4 | — | |
FWCVPCBOIZCNOC
|
7.1 | IC50 | 2 | — | |
ZWJWHZWSGHWFAU
|
7.0 | IC50 | 2 | — | |
QFEIXDQUGZUYQO
|
6.9 | IC50 | 2 | — | |
QPYPTVHTUUFCJA
|
6.9 | IC50 | 2 | — | |
IYCHKGRPYNYPKN
|
6.5 | IC50 | 2 | — | |
GDNLVYWUVLSRJS
|
6.4 | Ki | 2 | — | |
OIPHUNISSZOMOG
|
6.4 | IC50 | 2 | — | |
DEWWXXMPBVZWTK
|
6.4 | IC50 | 2 | — | |
PCEGZCIJFQEUCW
|
6.4 | IC50 | 2 | — | |
QCNFRMVLPRKVBE
|
6.4 | IC50 | 2 | — | |
JSRBFPUGRGUQAI
|
6.3 | IC50 | 2 | — | |
ZGYWPGJYSJGPSB
|
6.3 | IC50 | 2 | — | |
LEGLTUJEHNJTIU
|
6.3 | IC50 | 2 | — | |
NZZFTTUZHHXQNY
|
6.3 | IC50 | 2 | — | |
PXKJKJCVYAEING
|
6.3 | IC50 | 2 | — | |
VOGFUJITTYTSEN
|
6.3 | IC50 | 2 | — | |
DZFHIUIZHFJFJE
|
6.3 | IC50 | 2 | — | |
RXMIXLORYURKCC
|
6.3 | IC50 | 2 | — | |
IVAVBLJZUKLUKH
|
6.2 | IC50 | 2 | — | |
UMSCZQBVWJHNFS
|
6.2 | IC50 | 2 | — | |
KNTXAVRHVYGJNW
|
6.2 | Ki | 2 | — | |
WRPGTEHOQWGUNC
|
6.2 | IC50 | 2 | — | |
VGZDJPMEXJUALY
|
6.1 | IC50 | 2 | — | |
RDXIGULVOZRKTD
|
6.0 | IC50 | 2 | — | |
TVKJCTARWUXOGZ
|
6.0 | Ki | 2 | — |