Target Details
UniProt ACP18405
Gene SymbolSRD5A1
Protein Name3-oxo-5-alpha-steroid 4-dehydrogenase 1
OrganismHomo sapiens
Entry Name
Organism Category Human
Pfam Domains PF02544 (Steroid_dh)
UniProt
Summary
  • Multi-target molecules 250
  • Clinical molecules 194
  • Avg pChEMBL 7.55
KEGG Pathways (2)
Top Co-occurrence Targets
Active Molecules (250)
InChIKey pChEMBL Type Targets Clinical
CHSQDJYRTBPAPX 9.9 Ki 4 Yes
BLEPQUNBCNDAPZ 9.7 Ki 2 —
JMIULZVWYMHHAO 9.7 Ki 2 —
MYYLULRVFXQYTI 9.7 Ki 2 —
NHMZOHFSSLVUJN 9.7 Ki 4 Yes
VEBGFZDIXSWIAZ 9.7 Ki 4 Yes
HCXSUZWCTCKJCT 9.5 Ki 4 Yes
MGWINPKOOOQWKY 9.5 Ki 2 —
CHXGEQWNFRZIOC 9.4 Ki 3 Yes
XUTZDXHKQDPUMA 9.3 IC50 2 —
ZRKMLXOVZYKUKU 9.3 Ki 3 Yes
FAGYSQSLIMHWHR 9.2 IC50 4 Yes
KIRJENQTDJNKGS 9.2 Ki 2 —
JQKANSBWFRBIRJ 9.1 IC50 4 Yes
XUTZDXHKQDPUMA 9.1 IC50 4 Yes
LHFFYCSBQXAENY 9.0 Ki 3 Yes
UYRALUALZCKFQB 9.0 Ki 3 Yes
YNNSWQDWQWPZOM 8.9 Ki 3 Yes
ZDUXGHLKBYRGNA 8.8 Ki 3 Yes
SXKLCKROMAELSQ 8.8 IC50 4 Yes
QASMLJURBZXYNW 8.8 IC50 4 Yes
QASMLJURBZXYNW 8.8 IC50 4 Yes
PVJNSDNELNARLT 8.7 IC50 4 Yes
HMRMTWUTVVIJSI 8.6 IC50 4 Yes
JWJOTENAMICLJG 8.6 IC50 4 Yes
MOQPSDNFBMURQO 8.6 IC50 4 Yes
DHZJVHCWDITFSE 8.6 IC50 4 Yes
WJSKTFAFISQDLB 8.6 IC50 4 Yes
MASOXJRADXYGSF 8.6 IC50 4 Yes
FGXXHFWGZTYOIF 8.5 IC50 4 Yes
GNWBLLYJQXKPIP 8.5 IC50 4 Yes
GNWBLLYJQXKPIP 8.5 Ki 2 —
HSLBNURTOUIFTB 8.5 Ki 3 Yes
NBBYAAZSMXQCCA 8.5 Ki 3 Yes
ZJWSEMRSCBPWPD 8.5 Ki 4 Yes
SKUMRKIUNUEXKH 8.5 Ki 2 —
ZWYOUKDNWVHYPO 8.5 IC50 3 Yes
ZWYOUKDNWVHYPO 8.5 IC50 3 Yes
DJRXLRCSNPWILL 8.5 Ki 3 Yes
WWMGAPRXPIKGFI 8.5 IC50 4 Yes
CBUXLBQVPVOWAL 8.4 Ki 3 Yes
IAOYQLOKTBWIQA 8.4 Ki 3 Yes
MRGJPQCXQRRGHN 8.4 Ki 3 Yes
QLJSQRVXMOGBQC 8.4 Ki 3 Yes
GNWBLLYJQXKPIP 8.4 IC50 4 Yes
DQDHQICCPRPMJN 8.4 Ki 3 Yes
YCLGPSTWDAETKY 8.3 Ki 3 Yes
BRHIXTUOQVNYTA 8.3 Ki 3 Yes
LKDQSNWQLXOUNX 8.3 Ki 3 Yes
GPGLGVIBAVITFL 8.2 IC50 3 Yes
2D structure