Target Details
| UniProt AC | P17858 |
|---|---|
| Gene Symbol | PFKL |
| Protein Name | ATP-dependent 6-phosphofructokinase, liver type |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF00365 (PFK) |
Summary
- Multi-target molecules 1
- Clinical molecules 0
- Avg pChEMBL 7.47
KEGG Pathways (13)
- AMPK signaling pathway
- Biosynthesis of amino acids
- Carbon metabolism
- Central carbon metabolism in cancer
- Fructose and mannose metabolism
- Galactose metabolism
- Glucagon signaling pathway
- Glycolysis / Gluconeogenesis
- HIF-1 signaling pathway
- Metabolic pathways
- Pentose phosphate pathway
- RNA degradation
- Thyroid hormone signaling pathway
Active Molecules (1)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
MWKSRKSEWLRPBL
|
7.5 | Kd | 1075 | — |