Target Details
| UniProt AC | P17301 |
|---|---|
| Gene Symbol | ITGA2 |
| Protein Name | Integrin alpha-2 |
| Organism | Homo sapiens |
| Entry Name | |
| Organism Category | Human |
| Pfam Domains | PF01839 (FG-GAP) PF20805 (Integrin_A_Ig_2) PF20806 (Integrin_A_Ig_3) PF00092 (VWA) |
Summary
- Multi-target molecules 65
- Clinical molecules 0
- Avg pChEMBL 7.24
KEGG Pathways (17)
- Arrhythmogenic right ventricular cardiomyopathy
- Cytoskeleton in muscle cells
- Dilated cardiomyopathy
- ECM-receptor interaction
- Focal adhesion
- Hematopoietic cell lineage
- Human papillomavirus infection
- Hypertrophic cardiomyopathy
- Integrin signaling
- PI3K-Akt signaling pathway
- Pathways in cancer
- Phagosome
- Platelet activation
- Proteoglycans in cancer
- Regulation of actin cytoskeleton
- Small cell lung cancer
- Virion - Rotavirus
Associated Diseases (2)
Active Molecules (65)
| InChIKey | pChEMBL | Type | Targets | Clinical | |
|---|---|---|---|---|---|
KCPZTHQHJHVUCK
|
9.2 | IC50 | 3 | — | |
VHKHAQYPTPVIAP
|
9.1 | IC50 | 3 | — | |
OCNALRIBAIFGLP
|
9.0 | IC50 | 3 | — | |
GXEBJYPYNMZCSZ
|
8.4 | IC50 | 2 | — | |
XXVHVXVVXGOJQZ
|
8.4 | IC50 | 4 | — | |
FWTBEVQUAGZEME
|
8.3 | IC50 | 2 | — | |
HWRXVANHVCXVHA
|
8.3 | IC50 | 3 | — | |
WDIWMXJMARYXEG
|
8.2 | IC50 | 2 | — | |
PDZPUQQVGSDNOJ
|
8.2 | IC50 | 3 | — | |
OFMXNBIPYOLGBH
|
8.2 | IC50 | 3 | — | |
UWKPPOAXIFLKJM
|
8.2 | IC50 | 3 | — | |
PYELMOFQPMMHKM
|
8.2 | IC50 | 3 | — | |
JCOVTLVBRHTAIH
|
8.1 | IC50 | 2 | — | |
MPYXISYAFIYYRD
|
8.1 | IC50 | 2 | — | |
JXRHFSZNVUPMJD
|
8.0 | IC50 | 3 | — | |
FXUVHANSMHURSV
|
7.9 | IC50 | 2 | — | |
XKLHCUGVLCGKKX
|
7.9 | IC50 | 2 | — | |
XKLHCUGVLCGKKX
|
7.9 | IC50 | 2 | — | |
URLNLDYQABPXQL
|
7.8 | IC50 | 2 | — | |
DIZOQKOFMWJGAN
|
7.7 | IC50 | 2 | — | |
PDZPUQQVGSDNOJ
|
7.6 | IC50 | 3 | — | |
PYOAJLYUVZTXSE
|
7.6 | IC50 | 2 | — | |
YAAYYZAARZCUQN
|
7.6 | IC50 | 3 | — | |
VGPKJRDGGNBIGH
|
7.5 | IC50 | 2 | — | |
COKMIXFXJJXBQG
|
7.5 | IC50 | 4 | — | |
FCYAEWBZIOBHAX
|
7.5 | IC50 | 2 | — | |
CRKRBHBMNNGEOT
|
7.4 | IC50 | 2 | — | |
XTQXPPMGGYXNQD
|
7.4 | IC50 | 3 | — | |
NYGQATJDYMZDLT
|
7.4 | IC50 | 3 | — | |
PIRIIWBJGLBSQS
|
7.4 | IC50 | 2 | — | |
ACPGEFYNFSMQSQ
|
7.3 | IC50 | 3 | — | |
ZXRLVUCOFJPEID
|
7.2 | IC50 | 2 | — | |
CMAJZWVPCYATQW
|
7.1 | IC50 | 2 | — | |
ITNCYPYTFKVCFI
|
7.0 | IC50 | 3 | — | |
WQVOUYNTLLCWOA
|
7.0 | IC50 | 2 | — | |
CLQFGFMZICVAGP
|
7.0 | IC50 | 2 | — | |
FPWWHFZBMPQJMS
|
7.0 | IC50 | 3 | — | |
QJFRIWWRGGAVHB
|
7.0 | IC50 | 2 | — | |
NHZAXNNFKILNCX
|
6.9 | IC50 | 2 | — | |
FWOZSFGPVXYBNW
|
6.9 | IC50 | 2 | — | |
KXYKFCPLPVZYME
|
6.8 | IC50 | 2 | — | |
MNPUWEMPSQZKGR
|
6.8 | IC50 | 3 | — | |
KBMXMIHYKVQSHP
|
6.8 | IC50 | 2 | — | |
BAWJRRUGVCVUHL
|
6.8 | IC50 | 2 | — | |
CRJZTXVLJWNQDW
|
6.8 | IC50 | 2 | — | |
ZVQLKFJNEALOSW
|
6.8 | IC50 | 2 | — | |
JTVWJXUGGJTGDA
|
6.7 | IC50 | 4 | — | |
PRQVABJPYZFCOM
|
6.6 | IC50 | 2 | — | |
BHJOXRDKAUNWMH
|
6.6 | IC50 | 3 | — | |
GXWGJFIDBBUABQ
|
6.6 | IC50 | 2 | — |